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Species-specific metabolic reprogramming in human and mouse microglia during inflammatory pathway induction.
Sabogal-Guáqueta AM, Marmolejo-Garza A, Trombetta-Lima M, Oun A, Hunneman J, Chen T, Koistinaho J, Lehtonen S, Kortholt A, Wolters JC, Bakker BM, Eggen BJL, Boddeke E, Dolga A. Sabogal-Guáqueta AM, et al. Among authors: koistinaho j. Nat Commun. 2023 Oct 13;14(1):6454. doi: 10.1038/s41467-023-42096-7. Nat Commun. 2023. PMID: 37833292 Free PMC article.
Human iPSC-derived microglia carrying the LRRK2-G2019S mutation show a Parkinson's disease related transcriptional profile and function.
Ohtonen S, Giudice L, Jäntti H, Fazaludeen MF, Shakirzyanova A, Gómez-Budia M, Välimäki NN, Niskanen J, Korvenlaita N, Fagerlund I, Koistinaho J, Amiry-Moghaddam M, Savchenko E, Roybon L, Lehtonen Š, Korhonen P, Malm T. Ohtonen S, et al. Among authors: koistinaho j. Sci Rep. 2023 Dec 13;13(1):22118. doi: 10.1038/s41598-023-49294-9. Sci Rep. 2023. PMID: 38092815 Free PMC article.
Particulate matter from car exhaust alters function of human iPSC-derived microglia.
Jäntti H, Jonk S, Gómez Budia M, Ohtonen S, Fagerlund I, Fazaludeen MF, Aakko-Saksa P, Pebay A, Lehtonen Š, Koistinaho J, Kanninen KM, Jalava PI, Malm T, Korhonen P. Jäntti H, et al. Among authors: koistinaho j. Part Fibre Toxicol. 2024 Feb 15;21(1):6. doi: 10.1186/s12989-024-00564-y. Part Fibre Toxicol. 2024. PMID: 38360668 Free PMC article.
Astrocytes Regulate Neuronal Network Burst Frequency Through NMDA Receptors in a Species- and Donor-Specific Manner.
Räsänen N, Tiihonen J, Koskuvi M, Lehtonen Š, Jalkanen N, Karmila N, Weert I, Vaurio O, Ojansuu I, Lähteenvuo M, Pietiläinen O, Koistinaho J. Räsänen N, et al. Among authors: koistinaho j. Biol Psychiatry Glob Open Sci. 2024 Apr 3;4(4):100313. doi: 10.1016/j.bpsgos.2024.100313. eCollection 2024 Jul. Biol Psychiatry Glob Open Sci. 2024. PMID: 38706704 Free PMC article.
Alzheimer's disease brain endothelial-like cells reveal differential drug transporter expression and modulation by potentially therapeutic focused ultrasound.
Chaves JCS, Wasielewska JM, Cuní-López C, Rantanen LM, Lee S, Koistinaho J, White AR, Oikari LE. Chaves JCS, et al. Among authors: koistinaho j. Neurotherapeutics. 2024 Jan;21(1):e00299. doi: 10.1016/j.neurot.2023.10.009. Epub 2023 Dec 19. Neurotherapeutics. 2024. PMID: 38241156 Free PMC article.
ciRS-7 and miR-7 regulate ischemia-induced neuronal death via glutamatergic signaling.
Scoyni F, Sitnikova V, Giudice L, Korhonen P, Trevisan DM, Hernandez de Sande A, Gomez-Budia M, Giniatullina R, Ugidos IF, Dhungana H, Pistono C, Korvenlaita N, Välimäki NN, Kangas SM, Hiltunen AE, Gribchenko E, Kaikkonen-Määttä MU, Koistinaho J, Ylä-Herttuala S, Hinttala R, Venø MT, Su J, Stoffel M, Schaefer A, Rajewsky N, Kjems J, LaPierre MP, Piwecka M, Jolkkonen J, Giniatullin R, Hansen TB, Malm T. Scoyni F, et al. Among authors: koistinaho j. Cell Rep. 2024 Mar 26;43(3):113862. doi: 10.1016/j.celrep.2024.113862. Epub 2024 Mar 5. Cell Rep. 2024. PMID: 38446664 Free article.
283 results