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Molecular mechanism of the wake-promoting agent TAK-925.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Among authors: koike t. Nat Commun. 2022 May 25;13(1):2902. doi: 10.1038/s41467-022-30601-3. Nat Commun. 2022. PMID: 35614071 Free PMC article.
Design, Synthesis, and Evaluation of 11C-Labeled 3-Acetyl-Indole Derivatives as a Novel Positron Emission Tomography Imaging Agent for Diacylglycerol Kinase Gamma (DGKγ) in Brain.
Hattori Y, Yamasaki T, Ohashi T, Miyanohana Y, Kusumoto T, Maeda R, Miyamoto M, Debori Y, Hata A, Zhang Y, Wakizaka H, Wakabayashi T, Fujinaga M, Yamashita R, Zhang MR, Koike T. Hattori Y, et al. Among authors: koike t. J Med Chem. 2021 Aug 26;64(16):11990-12002. doi: 10.1021/acs.jmedchem.1c00584. Epub 2021 Aug 4. J Med Chem. 2021. PMID: 34347478
Reply to: The G protein preference of orexin receptors is currently an unresolved issue.
Yin J, Kang Y, McGrath AP, Chapman K, Sjodt M, Kimura E, Okabe A, Koike T, Miyanohana Y, Shimizu Y, Rallabandi R, Lian P, Bai X, Flinspach M, De Brabander JK, Rosenbaum DM. Yin J, et al. Among authors: koike t. Nat Commun. 2023 Jun 1;14(1):3163. doi: 10.1038/s41467-023-38765-2. Nat Commun. 2023. PMID: 37264001 Free PMC article. No abstract available.
Design, Synthesis, and Evaluation of (4 R)-1-{3-[2-(18F)Fluoro-4-methylpyridin-3-yl]phenyl}-4-[4-(1,3-thiazol-2-ylcarbonyl)piperazin-1-yl]pyrrolidin-2-one ([18F]T-401) as a Novel Positron-Emission Tomography Imaging Agent for Monoacylglycerol Lipase.
Hattori Y, Aoyama K, Maeda J, Arimura N, Takahashi Y, Sasaki M, Fujinaga M, Seki C, Nagai Y, Kawamura K, Yamasaki T, Zhang MR, Higuchi M, Koike T. Hattori Y, et al. Among authors: koike t. J Med Chem. 2019 Mar 14;62(5):2362-2375. doi: 10.1021/acs.jmedchem.8b01576. Epub 2019 Feb 26. J Med Chem. 2019. PMID: 30753069
Design and synthesis of aryl-piperidine derivatives as potent and selective PET tracers for cholesterol 24-hydroxylase (CH24H).
Ikeda S, Kajita Y, Miyamoto M, Matsumiya K, Ishii T, Nishi T, Gay SC, Lane W, Constantinescu CC, Alagille D, Papin C, Tamagnan G, Kuroita T, Koike T. Ikeda S, et al. Among authors: koike t. Eur J Med Chem. 2022 Oct 5;240:114612. doi: 10.1016/j.ejmech.2022.114612. Epub 2022 Jul 14. Eur J Med Chem. 2022. PMID: 35863274 Free article.
2,581 results