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Downregulation of the FTO m6A RNA demethylase promotes EMT-mediated progression of epithelial tumors and sensitivity to Wnt inhibitors.
Jeschke J, Collignon E, Al Wardi C, Krayem M, Bizet M, Jia Y, Garaud S, Wimana Z, Calonne E, Hassabi B, Morandini R, Deplus R, Putmans P, Dube G, Singh NK, Koch A, Shostak K, Rizzotto L, Ross RL, Desmedt C, Bareche Y, Rothé F, Lehmann-Che J, Duterque-Coquillaud M, Leroy X, Menschaert G, Teixeira L, Guo M, Limbach PA, Close P, Chariot A, Leucci E, Ghanem G, Yuan BF, Willard-Gallo K, Sotiriou C, Marine JC, Fuks F. Jeschke J, et al. Among authors: koch a. Nat Cancer. 2021 Jun;2(6):611-628. doi: 10.1038/s43018-021-00223-7. Epub 2021 Jun 23. Nat Cancer. 2021. PMID: 35121941 Free PMC article.
DNA methylation-based immune response signature improves patient diagnosis in multiple cancers.
Jeschke J, Bizet M, Desmedt C, Calonne E, Dedeurwaerder S, Garaud S, Koch A, Larsimont D, Salgado R, Van den Eynden G, Willard Gallo K, Bontempi G, Defrance M, Sotiriou C, Fuks F. Jeschke J, et al. Among authors: koch a. J Clin Invest. 2017 Aug 1;127(8):3090-3102. doi: 10.1172/JCI91095. Epub 2017 Jul 17. J Clin Invest. 2017. PMID: 28714863 Free PMC article.
MEXPRESS update 2019.
Koch A, Jeschke J, Van Criekinge W, van Engeland M, De Meyer T. Koch A, et al. Nucleic Acids Res. 2019 Jul 2;47(W1):W561-W565. doi: 10.1093/nar/gkz445. Nucleic Acids Res. 2019. PMID: 31114869 Free PMC article.
A proteogenomics approach integrating proteomics and ribosome profiling increases the efficiency of protein identification and enables the discovery of alternative translation start sites.
Koch A, Gawron D, Steyaert S, Ndah E, Crappé J, De Keulenaer S, De Meester E, Ma M, Shen B, Gevaert K, Van Criekinge W, Van Damme P, Menschaert G. Koch A, et al. Proteomics. 2014 Dec;14(23-24):2688-98. doi: 10.1002/pmic.201400180. Epub 2014 Oct 2. Proteomics. 2014. PMID: 25156699 Free PMC article.
Deep proteome coverage based on ribosome profiling aids mass spectrometry-based protein and peptide discovery and provides evidence of alternative translation products and near-cognate translation initiation events.
Menschaert G, Van Criekinge W, Notelaers T, Koch A, Crappé J, Gevaert K, Van Damme P. Menschaert G, et al. Among authors: koch a. Mol Cell Proteomics. 2013 Jul;12(7):1780-90. doi: 10.1074/mcp.M113.027540. Epub 2013 Feb 21. Mol Cell Proteomics. 2013. PMID: 23429522 Free PMC article.
PROTEOFORMER: deep proteome coverage through ribosome profiling and MS integration.
Crappé J, Ndah E, Koch A, Steyaert S, Gawron D, De Keulenaer S, De Meester E, De Meyer T, Van Criekinge W, Van Damme P, Menschaert G. Crappé J, et al. Among authors: koch a. Nucleic Acids Res. 2015 Mar 11;43(5):e29. doi: 10.1093/nar/gku1283. Epub 2014 Dec 15. Nucleic Acids Res. 2015. PMID: 25510491 Free PMC article.
Differential Orthopedia Homeobox expression in pulmonary carcinoids is associated with changes in DNA methylation.
Moonen L, Mangiante L, Leunissen DJG, Lap LMV, Gabriel A, Hillen LM, Roemen GM, Koch A, van Engeland M, Dingemans AC, Foll M, Alcala N, Fernandez-Cuesta L, Derks JL, Speel EM. Moonen L, et al. Among authors: koch a. Int J Cancer. 2022 Jun 15;150(12):1987-1997. doi: 10.1002/ijc.33939. Epub 2022 Feb 16. Int J Cancer. 2022. PMID: 35076935 Free PMC article.
Analysis of DNA methylation in cancer: location revisited.
Koch A, Joosten SC, Feng Z, de Ruijter TC, Draht MX, Melotte V, Smits KM, Veeck J, Herman JG, Van Neste L, Van Criekinge W, De Meyer T, van Engeland M. Koch A, et al. Nat Rev Clin Oncol. 2018 Jul;15(7):459-466. doi: 10.1038/s41571-018-0004-4. Nat Rev Clin Oncol. 2018. PMID: 29666440 Review.
2,965 results