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PGE2 limits effector expansion of tumour-infiltrating stem-like CD8+ T cells.
Lacher SB, Dörr J, de Almeida GP, Hönninger J, Bayerl F, Hirschberger A, Pedde AM, Meiser P, Ramsauer L, Rudolph TJ, Spranger N, Morotti M, Grimm AJ, Jarosch S, Oner A, Gregor L, Lesch S, Michaelides S, Fertig L, Briukhovetska D, Majed L, Stock S, Busch DH, Buchholz VR, Knolle PA, Zehn D, Dangaj Laniti D, Kobold S, Böttcher JP. Lacher SB, et al. Among authors: kobold s. Nature. 2024 May;629(8011):417-425. doi: 10.1038/s41586-024-07254-x. Epub 2024 Apr 24. Nature. 2024. PMID: 38658748 Free PMC article.
Comparative performance of scFv-based anti-BCMA CAR formats for improved T cell therapy in multiple myeloma.
Stock S, Fertig L, Gottschlich A, Dörr J, Märkl F, Majed L, Menkhoff VD, Grünmeier R, Rejeski K, Cordas Dos Santos DM, Theurich S, von Bergwelt-Baildon M, Endres S, Subklewe M, Kobold S. Stock S, et al. Among authors: kobold s. Cancer Immunol Immunother. 2024 Apr 17;73(6):100. doi: 10.1007/s00262-024-03688-4. Cancer Immunol Immunother. 2024. PMID: 38630291 Free PMC article.
Efficient Chimeric Antigen Receptor T-Cell Generation Starting with Leukoreduction System Chambers of Thrombocyte Apheresis Sets.
Xhaxho S, Chen-Wichmann L, Kreissig S, Windisch R, Gottschlich A, Nandi S, Schabernack S, Kohler I, Kellner C, Kobold S, Humpe A, Wichmann C. Xhaxho S, et al. Among authors: kobold s. Transfus Med Hemother. 2023 Aug 30;51(2):111-118. doi: 10.1159/000532130. eCollection 2024 Apr. Transfus Med Hemother. 2023. PMID: 38584695 Free PMC article.
CAR T cells for solid tumors - developments to watch in 2023.
Trefny MP, Kobold S. Trefny MP, et al. Among authors: kobold s. Expert Opin Biol Ther. 2024 Apr;24(4):207-211. doi: 10.1080/14712598.2024.2334399. Epub 2024 Mar 25. Expert Opin Biol Ther. 2024. PMID: 38526025 No abstract available.
Mutation-specific CAR T cells as precision therapy for IGLV3-21R110 expressing high-risk chronic lymphocytic leukemia.
Märkl F, Schultheiß C, Ali M, Chen SS, Zintchenko M, Egli L, Mietz J, Chijioke O, Paschold L, Spajic S, Holtermann A, Dörr J, Stock S, Zingg A, Läubli H, Piseddu I, Anz D, Minden MD, Zhang T, Nerreter T, Hudecek M, Minguet S, Chiorazzi N, Kobold S, Binder M. Märkl F, et al. Among authors: kobold s. Nat Commun. 2024 Feb 2;15(1):993. doi: 10.1038/s41467-024-45378-w. Nat Commun. 2024. PMID: 38307904 Free PMC article.
Major immunophenotypic abnormalities in patients with primary adrenal insufficiency of different etiology.
Nowotny HF, Marchant Seiter T, Ju J, Gottschlich A, Schneider H, Zopp S, Vogel F, Tschaidse L, Auer MK, Lottspeich C, Kobold S, Rothenfusser S, Beuschlein F, Reincke M, Braun L, Reisch N. Nowotny HF, et al. Among authors: kobold s. Front Immunol. 2023 Nov 15;14:1275828. doi: 10.3389/fimmu.2023.1275828. eCollection 2023. Front Immunol. 2023. PMID: 38045693 Free PMC article.
Mitochondrial dysfunction promotes the transition of precursor to terminally exhausted T cells through HIF-1α-mediated glycolytic reprogramming.
Wu H, Zhao X, Hochrein SM, Eckstein M, Gubert GF, Knöpper K, Mansilla AM, Öner A, Doucet-Ladevèze R, Schmitz W, Ghesquière B, Theurich S, Dudek J, Gasteiger G, Zernecke A, Kobold S, Kastenmüller W, Vaeth M. Wu H, et al. Among authors: kobold s. Nat Commun. 2023 Oct 27;14(1):6858. doi: 10.1038/s41467-023-42634-3. Nat Commun. 2023. PMID: 37891230 Free PMC article.
Programmable multispecific DNA-origami-based T-cell engagers.
Wagenbauer KF, Pham N, Gottschlich A, Kick B, Kozina V, Frank C, Trninic D, Stömmer P, Grünmeier R, Carlini E, Tsiverioti CA, Kobold S, Funke JJ, Dietz H. Wagenbauer KF, et al. Among authors: kobold s. Nat Nanotechnol. 2023 Nov;18(11):1319-1326. doi: 10.1038/s41565-023-01471-7. Epub 2023 Aug 17. Nat Nanotechnol. 2023. PMID: 37591933 Free PMC article.
HDR-based CRISPR/Cas9-mediated Knockout of PD-L1 in C57BL/6 Mice.
Heeb LV, Taskoparan B, Katsoulas A, Beffinger M, Clavien PA, Kobold S, Gupta A, Berg JV. Heeb LV, et al. Among authors: kobold s. Bio Protoc. 2023 Jul 20;13(14):e4724. doi: 10.21769/BioProtoc.4724. eCollection 2023 Jul 20. Bio Protoc. 2023. PMID: 37497456 Free PMC article.
145 results