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Styryl quinazolinones and its ethynyl derivatives induce myeloid differentiation.
Radhakrishnan S, Syed R, Takei H, Kobayashi IS, Nakamura E, Sultana F, Kamal A, Tenen DG, Kobayashi SS. Radhakrishnan S, et al. Among authors: kobayashi ss, kobayashi is. Bioorg Med Chem Lett. 2019 Aug 15;29(16):2286-2289. doi: 10.1016/j.bmcl.2019.06.024. Epub 2019 Jun 20. Bioorg Med Chem Lett. 2019. PMID: 31278031 Free PMC article.
Alternative splicing of APOBEC3D generates functional diversity and its role as a DNA mutator.
Takei H, Fukuda H, Pan G, Yamazaki H, Matsumoto T, Kazuma Y, Fujii M, Nakayama S, Kobayashi IS, Shindo K, Yamashita R, Shirakawa K, Takaori-Kondo A, Kobayashi SS. Takei H, et al. Among authors: kobayashi ss, kobayashi is. Int J Hematol. 2020 Sep;112(3):395-408. doi: 10.1007/s12185-020-02904-y. Epub 2020 Jun 12. Int J Hematol. 2020. PMID: 32533515 Free PMC article.
EGFR-A763_Y764insFQEA Is a Unique Exon 20 Insertion Mutation That Displays Sensitivity to Approved and In-Development Lung Cancer EGFR Tyrosine Kinase Inhibitors.
Vasconcelos PENS, Gergis C, Viray H, Varkaris A, Fujii M, Rangachari D, VanderLaan PA, Kobayashi IS, Kobayashi SS, Costa DB. Vasconcelos PENS, et al. Among authors: kobayashi is. JTO Clin Res Rep. 2020 Sep;1(3):100051. doi: 10.1016/j.jtocrr.2020.100051. Epub 2020 May 13. JTO Clin Res Rep. 2020. PMID: 34104899 Free PMC article.
Single-Cell Analyses Reveal Diverse Mechanisms of Resistance to EGFR Tyrosine Kinase Inhibitors in Lung Cancer.
Kashima Y, Shibahara D, Suzuki A, Muto K, Kobayashi IS, Plotnick D, Udagawa H, Izumi H, Shibata Y, Tanaka K, Fujii M, Ohashi A, Seki M, Goto K, Tsuchihara K, Suzuki Y, Kobayashi SS. Kashima Y, et al. Among authors: kobayashi is. Cancer Res. 2021 Sep 15;81(18):4835-4848. doi: 10.1158/0008-5472.CAN-20-2811. Epub 2021 Jul 9. Cancer Res. 2021. PMID: 34247147 Free PMC article.
Suppression of multiple anti-apoptotic BCL2 family proteins recapitulates the effects of JAK2 inhibitors in JAK2V617F driven myeloproliferative neoplasms.
Takei H, Coelho-Silva JL, Tavares Leal C, Queiroz Arantes Rocha A, Mantello Bianco T, Welner RS, Mishima Y, Kobayashi IS, Mullally A, Lima K, Machado-Neto JA, Kobayashi SS, Lobo de Figueiredo-Pontes L. Takei H, et al. Among authors: kobayashi is. Cancer Sci. 2022 Feb;113(2):597-608. doi: 10.1111/cas.15210. Epub 2021 Dec 15. Cancer Sci. 2022. PMID: 34808021 Free PMC article.
NAD Modulates DNA Methylation and Cell Differentiation.
Ummarino S, Hausman C, Gaggi G, Rinaldi L, Bassal MA, Zhang Y, Seelam AJ, Kobayashi IS, Borchiellini M, Ebralidze AK, Ghinassi B, Trinh BQ, Kobayashi SS, Di Ruscio A. Ummarino S, et al. Among authors: kobayashi is. Cells. 2021 Nov 2;10(11):2986. doi: 10.3390/cells10112986. Cells. 2021. PMID: 34831209 Free PMC article.
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