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9,321 results

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Page 1
Discovery of DS-1971a, a Potent, Selective NaV1.7 Inhibitor.
Shinozuka T, Kobayashi H, Suzuki S, Tanaka K, Karanjule N, Hayashi N, Tsuda T, Tokumaru E, Inoue M, Ueda K, Kimoto H, Domon Y, Takahashi S, Kubota K, Yokoyama T, Shimizugawa A, Koishi R, Fujiwara C, Asano D, Sakakura T, Takasuna K, Abe Y, Watanabe T, Kitano Y. Shinozuka T, et al. Among authors: kobayashi h. J Med Chem. 2020 Sep 24;63(18):10204-10220. doi: 10.1021/acs.jmedchem.0c00259. Epub 2020 May 26. J Med Chem. 2020. PMID: 32392056
Anxiolytic-like effects of mirogabalin, a novel ligand for α2δ ligand of voltage-gated calcium channels, in rats repeatedly injected with acidic saline intramuscularly, as an experimental model of fibromyalgia.
Murasawa H, Kobayashi H, Yasuda SI, Saeki K, Domon Y, Arakawa N, Kubota K, Kitano Y. Murasawa H, et al. Among authors: kobayashi h. Pharmacol Rep. 2020 Jun;72(3):571-579. doi: 10.1007/s43440-020-00103-4. Epub 2020 Apr 8. Pharmacol Rep. 2020. PMID: 32270470
Mirogabalin, a novel ligand for α2δ subunit of voltage-gated calcium channels, improves cognitive impairments in repeated intramuscular acidic saline injection model rats, an experimental model of fibromyalgia.
Murasawa H, Pawlak A, Kobayashi H, Saeki K, Yasuda SI, Kitano Y. Murasawa H, et al. Among authors: kobayashi h. Biomed Pharmacother. 2021 Jul;139:111647. doi: 10.1016/j.biopha.2021.111647. Epub 2021 Apr 30. Biomed Pharmacother. 2021. PMID: 33940507 Free article.
Epidemiology, microbiology, and diagnosis of infection in diabetic ketoacidosis and hyperosmolar hyperglycemic syndrome: A multicenter retrospective observational study.
Takahashi K, Uenishi N, Sanui M, Uchino S, Yonezawa N, Takei T, Nishioka N, Kobayashi H, Otaka S, Yamamoto K, Yasuda H, Kosaka S, Tokunaga H, Fujiwara N, Kondo T, Ishida T, Komatsu T, Endo K, Moriyama T, Oyasu T, Hayakawa M, Hoshino A, Matsuyama T, Miyamoto Y, Yanagisawa A, Wakabayashi T, Ueda T, Komuro T, Sugimoto T, Sasabuchi Y. Takahashi K, et al. Among authors: kobayashi h. Diabetes Res Clin Pract. 2024 May 19:111713. doi: 10.1016/j.diabres.2024.111713. Online ahead of print. Diabetes Res Clin Pract. 2024. PMID: 38772502
SDHAF1 confers metabolic resilience to aging hematopoietic stem cells by promoting mitochondrial ATP production.
Watanuki S, Kobayashi H, Sugiura Y, Yamamoto M, Karigane D, Shiroshita K, Sorimachi Y, Morikawa T, Fujita S, Shide K, Haraguchi M, Tamaki S, Mikawa T, Kondoh H, Nakano H, Sumiyama K, Nagamatsu G, Goda N, Okamoto S, Nakamura-Ishizu A, Shimoda K, Suematsu M, Suda T, Takubo K. Watanuki S, et al. Among authors: kobayashi h. Cell Stem Cell. 2024 May 14:S1934-5909(24)00176-0. doi: 10.1016/j.stem.2024.04.023. Online ahead of print. Cell Stem Cell. 2024. PMID: 38772377
Isobutyric acid enhances the anti-tumour effect of anti-PD-1 antibody.
Murayama M, Hosonuma M, Kuramasu A, Kobayashi S, Sasaki A, Baba Y, Narikawa Y, Toyoda H, Isobe J, Funayama E, Tajima K, Sasaki A, Maruyama Y, Yamazaki Y, Shida M, Hamada K, Hirasawa Y, Tsurui T, Ariizumi H, Ishiguro T, Suzuki R, Ohkuma R, Kubota Y, Horiike A, Sambe T, Tsuji M, Wada S, Kobayashi S, Shimane T, Tsunoda T, Kobayashi H, Kiuchi Y, Yoshimura K. Murayama M, et al. Among authors: kobayashi h. Sci Rep. 2024 May 17;14(1):11325. doi: 10.1038/s41598-024-59677-1. Sci Rep. 2024. PMID: 38760458 Free PMC article.
Aberrant CHCHD2-associated mitochondriopathy in Kii ALS/PDC astrocytes.
Leventoux N, Morimoto S, Ishikawa M, Nakamura S, Ozawa F, Kobayashi R, Watanabe H, Supakul S, Okamoto S, Zhou Z, Kobayashi H, Kato C, Hirokawa Y, Aiba I, Takahashi S, Shibata S, Takao M, Yoshida M, Endo F, Yamanaka K, Kokubo Y, Okano H. Leventoux N, et al. Among authors: kobayashi h. Acta Neuropathol. 2024 May 15;147(1):84. doi: 10.1007/s00401-024-02734-w. Acta Neuropathol. 2024. PMID: 38750212
9,321 results