Koštrun S - Search Results

1

Modeling cellular pharmacokinetics of 14- and 15-membered macrolides with physicochemical properties.

Stepanić V, Koštrun S, Malnar I, Hlevnjak M, Butković K, Ćaleta I, Dukši M, Kragol G, Makaruha-Stegić O, Mikac L, Ralić J, Tatić I, Tavčar B, Valko K, Zulfikari S, Munić V. Stepanić V, et al. Among authors: kostrun s. J Med Chem. 2011 Feb 10;54(3):719-33. doi: 10.1021/jm101317f. Epub 2011 Jan 5. J Med Chem. 2011. PMID: 21207938

2

Synthesis, biological activity and molecular modeling studies of novel COX-1 inhibitors.

Martić M, Tatić I, Marković S, Kujundzić N, Kostrun S. Martić M, et al. Among authors: kostrun s. Eur J Med Chem. 2004 Feb;39(2):141-51. doi: 10.1016/j.ejmech.2003.11.011. Eur J Med Chem. 2004. PMID: 14987823

3

Systematic approach to understanding macrolide-ribosome interactions: NMR and modeling studies of oleandomycin and its derivatives.

Novak P, Tatić I, Tepes P, Kostrun S, Barber J. Novak P, et al. Among authors: kostrun s. J Phys Chem A. 2006 Jan 19;110(2):572-9. doi: 10.1021/jp0526243. J Phys Chem A. 2006. PMID: 16405329

4

Homology modeling of human Fyn kinase structure: discovery of rosmarinic acid as a new Fyn kinase inhibitor and in silico study of its possible binding modes.

Jelić D, Mildner B, Kostrun S, Nujić K, Verbanac D, Culić O, Antolović R, Brandt W. Jelić D, et al. Among authors: kostrun s. J Med Chem. 2007 Mar 22;50(6):1090-100. doi: 10.1021/jm0607202. Epub 2007 Feb 22. J Med Chem. 2007. PMID: 17315853

5

Discovery of novel ureas and thioureas of 3-decladinosyl-3-hydroxy 15-membered azalides active against efflux-mediated resistant Streptococcus pneumoniae.

Bukvić Krajačić M, Dumić M, Novak P, Cindrić M, Koštrun S, Fajdetić A, Alihodžić S, Brajša K, Kujundžić N. Bukvić Krajačić M, et al. Among authors: kostrun s. Bioorg Med Chem Lett. 2011 Jan 15;21(2):853-6. doi: 10.1016/j.bmcl.2010.11.079. Epub 2010 Nov 21. Bioorg Med Chem Lett. 2011. PMID: 21185182

6

Intensity of macrolide anti-inflammatory activity in J774A.1 cells positively correlates with cellular accumulation and phospholipidosis.

Munić V, Banjanac M, Koštrun S, Nujić K, Bosnar M, Marjanović N, Ralić J, Matijašić M, Hlevnjak M, Eraković Haber V. Munić V, et al. Among authors: kostrun s. Pharmacol Res. 2011 Sep;64(3):298-307. doi: 10.1016/j.phrs.2011.03.011. Epub 2011 Apr 5. Pharmacol Res. 2011. PMID: 21473915

7

Synthesis and activity of new macrolones: conjugates between 6(7)-(2'-aminoethyl)-amino-1-cyclopropyl-3-carboxylic acid (2'-hydroxyethyl) amides and 4″-propenoyl-azithromycin.

Kapić S, Fajdetić A, Koštrun S, Cikoš A, Paljetak HČ, Antolović R, Holmes DJ, Alihodžić S. Kapić S, et al. Among authors: kostrun s. Bioorg Med Chem. 2011 Dec 1;19(23):7270-80. doi: 10.1016/j.bmc.2011.07.011. Epub 2011 Jul 21. Bioorg Med Chem. 2011. PMID: 22041174

8

Physicochemical profile of macrolides and their comparison with small molecules.

Stepanić V, Ziher D, Gabelica-Marković V, Jelić D, Nunhuck S, Valko K, Koštrun S. Stepanić V, et al. Among authors: kostrun s. Eur J Med Chem. 2012 Jan;47(1):462-72. doi: 10.1016/j.ejmech.2011.11.016. Epub 2011 Nov 17. Eur J Med Chem. 2012. PMID: 22152985

9

N'-substituted-2'-O,3'-N-carbonimidoyl bridged macrolides: novel anti-inflammatory macrolides without antimicrobial activity.

Bosnar M, Kragol G, Koštrun S, Vujasinović I, Bošnjak B, Bencetić Mihaljević V, Marušić Ištuk Z, Kapić S, Hrvačić B, Brajša K, Tavčar B, Jelić D, Glojnarić I, Verbanac D, Culić O, Padovan J, Alihodžić S, Eraković Haber V, Spaventi R. Bosnar M, et al. Among authors: kostrun s. J Med Chem. 2012 Jul 12;55(13):6111-23. doi: 10.1021/jm300356u. Epub 2012 Jun 25. J Med Chem. 2012. PMID: 22697905

10

Structure-property relationship for cellular accumulation of macrolones in human polymorphonuclear leukocytes (PMNs).

Munić Kos V, Koštrun S, Fajdetić A, Bosnar M, Kelnerić Ž, Stepanić V, Eraković Haber V. Munić Kos V, et al. Among authors: kostrun s. Eur J Pharm Sci. 2013 May 13;49(2):206-19. doi: 10.1016/j.ejps.2013.02.019. Epub 2013 Mar 7. Eur J Pharm Sci. 2013. PMID: 23474356

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