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Cancer cells educate natural killer cells to a metastasis-promoting cell state.
Chan IS, Knútsdóttir H, Ramakrishnan G, Padmanaban V, Warrier M, Ramirez JC, Dunworth M, Zhang H, Jaffee EM, Bader JS, Ewald AJ. Chan IS, et al. Among authors: knutsdottir h. J Cell Biol. 2020 Sep 7;219(9):e202001134. doi: 10.1083/jcb.202001134. J Cell Biol. 2020. PMID: 32645139 Free PMC article.
An expanded universe of cancer targets.
Hahn WC, Bader JS, Braun TP, Califano A, Clemons PA, Druker BJ, Ewald AJ, Fu H, Jagu S, Kemp CJ, Kim W, Kuo CJ, McManus M, B Mills G, Mo X, Sahni N, Schreiber SL, Talamas JA, Tamayo P, Tyner JW, Wagner BK, Weiss WA, Gerhard DS; Cancer Target Discovery and Development Network. Hahn WC, et al. Cell. 2021 Mar 4;184(5):1142-1155. doi: 10.1016/j.cell.2021.02.020. Cell. 2021. PMID: 33667368 Free PMC article. Review.
Inhibition of phosphodiesterase type 9 reduces obesity and cardiometabolic syndrome in mice.
Mishra S, Sadagopan N, Dunkerly-Eyring B, Rodriguez S, Sarver DC, Ceddia RP, Murphy SA, Knutsdottir H, Jani VP, Ashok D, Oeing CU, O'Rourke B, Gangoiti JA, Sears DD, Wong GW, Collins S, Kass DA. Mishra S, et al. Among authors: knutsdottir h. J Clin Invest. 2021 Nov 1;131(21):e148798. doi: 10.1172/JCI148798. J Clin Invest. 2021. PMID: 34618683 Free PMC article.
Morphology-guided transcriptomic analysis of human pancreatic cancer organoids reveals microenvironmental signals that enhance invasion.
Jeong YJ, Knutsdottir H, Shojaeian F, Lerner MG, Wissler MF, Henriet E, Ng T, Datta S, Navarro-Serer B, Chianchiano P, Kinny-Köster B, Zimmerman JW, Stein-O'Brien G, Gaida MM, Eshleman JR, Lin MT, Fertig EJ, Ewald AJ, Bader JS, Wood LD. Jeong YJ, et al. Among authors: knutsdottir h. J Clin Invest. 2023 Apr 17;133(8):e162054. doi: 10.1172/JCI162054. J Clin Invest. 2023. PMID: 36881486 Free PMC article.
15 results