Knudsen BR - Search Results

1

DNA-based sensor for real-time measurement of the enzymatic activity of human topoisomerase I.

Marcussen LB, Jepsen ML, Kristoffersen EL, Franch O, Proszek J, Ho YP, Stougaard M, Knudsen BR. Marcussen LB, et al. Among authors: knudsen br. Sensors (Basel). 2013 Mar 25;13(4):4017-28. doi: 10.3390/s130404017. Sensors (Basel). 2013. PMID: 23529147 Free PMC article.

2

Residues within the N-terminal domain of human topoisomerase I play a direct role in relaxation.

Lisby M, Olesen JR, Skouboe C, Krogh BO, Straub T, Boege F, Velmurugan S, Martensen PM, Andersen AH, Jayaram M, Westergaard O, Knudsen BR. Lisby M, et al. Among authors: knudsen br. J Biol Chem. 2001 Jun 8;276(23):20220-7. doi: 10.1074/jbc.M010991200. Epub 2001 Mar 29. J Biol Chem. 2001. PMID: 11283003 Free article.

3

Recombinogenic flap ligation mediated by human topoisomerase I.

Andersen FF, Andersen KE, Kusk M, Frøhlich RF, Westergaard O, Andersen AH, Knudsen BR. Andersen FF, et al. Among authors: knudsen br. J Mol Biol. 2003 Jul 4;330(2):235-46. doi: 10.1016/s0022-2836(03)00593-x. J Mol Biol. 2003. PMID: 12823964

4

The transducer domain is important for clamp operation in human DNA topoisomerase IIalpha.

Oestergaard VH, Bjergbaek L, Skouboe C, Giangiacomo L, Knudsen BR, Andersen AH. Oestergaard VH, et al. Among authors: knudsen br. J Biol Chem. 2004 Jan 16;279(3):1684-91. doi: 10.1074/jbc.M309624200. Epub 2003 Oct 28. J Biol Chem. 2004. PMID: 14583603 Free article.

5

Regions within the N-terminal domain of human topoisomerase I exert important functions during strand rotation and DNA binding.

Frøhlich RF, Andersen FF, Westergaard O, Andersen AH, Knudsen BR. Frøhlich RF, et al. Among authors: knudsen br. J Mol Biol. 2004 Feb 6;336(1):93-103. doi: 10.1016/j.jmb.2003.12.007. J Mol Biol. 2004. PMID: 14741206

6

Hindering the strand passage reaction of human topoisomerase IIalpha without disturbing DNA cleavage, ATP hydrolysis, or the operation of the N-terminal clamp.

Oestergaard VH, Giangiacomo L, Bjergbaek L, Knudsen BR, Andersen AH. Oestergaard VH, et al. Among authors: knudsen br. J Biol Chem. 2004 Jul 2;279(27):28093-9. doi: 10.1074/jbc.M402120200. Epub 2004 Apr 28. J Biol Chem. 2004. PMID: 15123700 Free article.

7

Resolution of Holliday junction substrates by human topoisomerase I.

Hede MS, Petersen RL, Frøhlich RF, Krüger D, Andersen FF, Andersen AH, Knudsen BR. Hede MS, et al. Among authors: knudsen br. J Mol Biol. 2007 Jan 26;365(4):1076-92. doi: 10.1016/j.jmb.2006.10.050. Epub 2006 Oct 21. J Mol Biol. 2007. PMID: 17101150

8

Tryptophane-205 of human topoisomerase I is essential for camptothecin inhibition of negative but not positive supercoil removal.

Frøhlich RF, Veigaard C, Andersen FF, McClendon AK, Gentry AC, Andersen AH, Osheroff N, Stevnsner T, Knudsen BR. Frøhlich RF, et al. Among authors: knudsen br. Nucleic Acids Res. 2007;35(18):6170-80. doi: 10.1093/nar/gkm669. Epub 2007 Sep 7. Nucleic Acids Res. 2007. PMID: 17827209 Free PMC article.

9

Hairpin structures formed by alpha satellite DNA of human centromeres are cleaved by human topoisomerase IIalpha.

Jonstrup AT, Thomsen T, Wang Y, Knudsen BR, Koch J, Andersen AH. Jonstrup AT, et al. Among authors: knudsen br. Nucleic Acids Res. 2008 Nov;36(19):6165-74. doi: 10.1093/nar/gkn640. Epub 2008 Sep 29. Nucleic Acids Res. 2008. PMID: 18824478 Free PMC article.

10

Single-molecule detection of human topoisomerase I cleavage-ligation activity.

Stougaard M, Lohmann JS, Mancino A, Celik S, Andersen FF, Koch J, Knudsen BR. Stougaard M, et al. Among authors: knudsen br. ACS Nano. 2009 Jan 27;3(1):223-33. doi: 10.1021/nn800509b. ACS Nano. 2009. PMID: 19206270

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