Knowles TP - Search Results

1

Probing small molecule binding to amyloid fibrils.

Buell AK, Esbjörner EK, Riss PJ, White DA, Aigbirhio FI, Toth G, Welland ME, Dobson CM, Knowles TP. Buell AK, et al. Among authors: knowles tp. Phys Chem Chem Phys. 2011 Dec 7;13(45):20044-52. doi: 10.1039/c1cp22283j. Epub 2011 Oct 17. Phys Chem Chem Phys. 2011. PMID: 22006124 Review.

2

The component polypeptide chains of bovine insulin nucleate or inhibit aggregation of the parent protein in a conformation-dependent manner.

Devlin GL, Knowles TP, Squires A, McCammon MG, Gras SL, Nilsson MR, Robinson CV, Dobson CM, MacPhee CE. Devlin GL, et al. Among authors: knowles tp. J Mol Biol. 2006 Jul 7;360(2):497-509. doi: 10.1016/j.jmb.2006.05.007. Epub 2006 May 17. J Mol Biol. 2006. PMID: 16774767

3

Spatial persistence of angular correlations in amyloid fibrils.

Knowles TP, Smith JF, Craig A, Dobson CM, Welland ME. Knowles TP, et al. Phys Rev Lett. 2006 Jun 16;96(23):238301. doi: 10.1103/PhysRevLett.96.238301. Epub 2006 Jun 12. Phys Rev Lett. 2006. PMID: 16803412

4

Characterization of the nanoscale properties of individual amyloid fibrils.

Smith JF, Knowles TP, Dobson CM, Macphee CE, Welland ME. Smith JF, et al. Among authors: knowles tp. Proc Natl Acad Sci U S A. 2006 Oct 24;103(43):15806-11. doi: 10.1073/pnas.0604035103. Epub 2006 Oct 12. Proc Natl Acad Sci U S A. 2006. PMID: 17038504 Free PMC article.

5

Kinetics and thermodynamics of amyloid formation from direct measurements of fluctuations in fibril mass.

Knowles TP, Shu W, Devlin GL, Meehan S, Auer S, Dobson CM, Welland ME. Knowles TP, et al. Proc Natl Acad Sci U S A. 2007 Jun 12;104(24):10016-21. doi: 10.1073/pnas.0610659104. Epub 2007 May 31. Proc Natl Acad Sci U S A. 2007. PMID: 17540728 Free PMC article.

6

Characterisation of amyloid fibril formation by small heat-shock chaperone proteins human alphaA-, alphaB- and R120G alphaB-crystallins.

Meehan S, Knowles TP, Baldwin AJ, Smith JF, Squires AM, Clements P, Treweek TM, Ecroyd H, Tartaglia GG, Vendruscolo M, Macphee CE, Dobson CM, Carver JA. Meehan S, et al. Among authors: knowles tp. J Mol Biol. 2007 Sep 14;372(2):470-84. doi: 10.1016/j.jmb.2007.06.060. Epub 2007 Jun 29. J Mol Biol. 2007. PMID: 17662998

7

Measurement of amyloid fibril length distributions by inclusion of rotational motion in solution NMR diffusion measurements.

Baldwin AJ, Anthony-Cahill SJ, Knowles TP, Lippens G, Christodoulou J, Barker PD, Dobson CM. Baldwin AJ, et al. Among authors: knowles tp. Angew Chem Int Ed Engl. 2008;47(18):3385-7. doi: 10.1002/anie.200703915. Angew Chem Int Ed Engl. 2008. PMID: 18350531 No abstract available.

8

Position-dependent electrostatic protection against protein aggregation.

Buell AK, Tartaglia GG, Birkett NR, Waudby CA, Vendruscolo M, Salvatella X, Welland ME, Dobson CM, Knowles TP. Buell AK, et al. Among authors: knowles tp. Chembiochem. 2009 May 25;10(8):1309-12. doi: 10.1002/cbic.200900144. Chembiochem. 2009. PMID: 19415709

9

Biosensor-based label-free assays of amyloid growth.

White DA, Buell AK, Dobson CM, Welland ME, Knowles TP. White DA, et al. Among authors: knowles tp. FEBS Lett. 2009 Aug 20;583(16):2587-92. doi: 10.1016/j.febslet.2009.06.008. Epub 2009 Jun 11. FEBS Lett. 2009. PMID: 19523953 Free article. Review.

10

Imaging amyloid fibrils within cells using a Se-labelling strategy.

Porter AE, Knowles TP, Muller K, Meehan S, McGuire E, Skepper J, Welland ME, Dobson CM. Porter AE, et al. Among authors: knowles tp. J Mol Biol. 2009 Oct 2;392(4):868-71. doi: 10.1016/j.jmb.2009.07.061. Epub 2009 Jul 25. J Mol Biol. 2009. PMID: 19635483

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