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Page 1
Integrative gene network and functional analyses identify a prognostically relevant key regulator of metastasis in Ewing sarcoma.
Cidre-Aranaz F, Li J, Hölting TLB, Orth MF, Imle R, Kutschmann S, Ammirati G, Ceranski K, Carreño-Gonzalez MJ, Kasan M, Marchetto A, Funk CM, Bestvater F, Bersini S, Arrigoni C, Moretti M, Thiel U, Baumhoer D, Sahm F, Pfister SM, Hartmann W, Dirksen U, Romero-Pérez L, Banito A, Ohmura S, Musa J, Kirchner T, Knott MML, Grünewald TGP. Cidre-Aranaz F, et al. Among authors: knott mml. Mol Cancer. 2022 Jan 3;21(1):1. doi: 10.1186/s12943-021-01470-z. Mol Cancer. 2022. PMID: 34980141 Free PMC article. No abstract available.
Oncogenic hijacking of a developmental transcription factor evokes vulnerability toward oxidative stress in Ewing sarcoma.
Marchetto A, Ohmura S, Orth MF, Knott MML, Colombo MV, Arrigoni C, Bardinet V, Saucier D, Wehweck FS, Li J, Stein S, Gerke JS, Baldauf MC, Musa J, Dallmayer M, Romero-Pérez L, Hölting TLB, Amatruda JF, Cossarizza A, Henssen AG, Kirchner T, Moretti M, Cidre-Aranaz F, Sannino G, Grünewald TGP. Marchetto A, et al. Among authors: knott mml. Nat Commun. 2020 May 15;11(1):2423. doi: 10.1038/s41467-020-16244-2. Nat Commun. 2020. PMID: 32415069 Free PMC article.
Functional genomics identifies AMPD2 as a new prognostic marker for undifferentiated pleomorphic sarcoma.
Orth MF, Gerke JS, Knösel T, Altendorf-Hofmann A, Musa J, Alba-Rubio R, Stein S, Hölting TLB, Cidre-Aranaz F, Romero-Pérez L, Dallmayer M, Baldauf MC, Marchetto A, Sannino G, Knott MML, Wehweck F, Ohmura S, Li J, Hakozaki M, Kirchner T, Dandekar T, Butt E, Grünewald TGP. Orth MF, et al. Among authors: knott mml. Int J Cancer. 2019 Feb 15;144(4):859-867. doi: 10.1002/ijc.31903. Epub 2018 Dec 4. Int J Cancer. 2019. PMID: 30267407 Free article.
Gene expression and immunohistochemical analyses identify SOX2 as major risk factor for overall survival and relapse in Ewing sarcoma patients.
Sannino G, Marchetto A, Ranft A, Jabar S, Zacherl C, Alba-Rubio R, Stein S, Wehweck FS, Kiran MM, Hölting TLB, Musa J, Romero-Pérez L, Cidre-Aranaz F, Knott MML, Li J, Jürgens H, Sastre A, Alonso J, Da Silveira W, Hardiman G, Gerke JS, Orth MF, Hartmann W, Kirchner T, Ohmura S, Dirksen U, Grünewald TGP. Sannino G, et al. Among authors: knott mml. EBioMedicine. 2019 Sep;47:156-162. doi: 10.1016/j.ebiom.2019.08.002. Epub 2019 Aug 16. EBioMedicine. 2019. PMID: 31427232 Free PMC article.
Integrative clinical transcriptome analysis reveals TMPRSS2-ERG dependency of prognostic biomarkers in prostate adenocarcinoma.
Gerke JS, Orth MF, Tolkach Y, Romero-Pérez L, Wehweck FS, Stein S, Musa J, Knott MML, Hölting TLB, Li J, Sannino G, Marchetto A, Ohmura S, Cidre-Aranaz F, Müller-Nurasyid M, Strauch K, Stief C, Kristiansen G, Kirchner T, Buchner A, Grünewald TGP. Gerke JS, et al. Among authors: knott mml. Int J Cancer. 2020 Apr 1;146(7):2036-2046. doi: 10.1002/ijc.32792. Epub 2019 Nov 29. Int J Cancer. 2020. PMID: 31732966 Free article.
Ewing Sarcoma-Specific (Re)expression Models.
Knott MML, Cidre-Aranaz F. Knott MML, et al. Methods Mol Biol. 2021;2226:119-138. doi: 10.1007/978-1-0716-1020-6_9. Methods Mol Biol. 2021. PMID: 33326097
Translational evidence for RRM2 as a prognostic biomarker and therapeutic target in Ewing sarcoma.
Ohmura S, Marchetto A, Orth MF, Li J, Jabar S, Ranft A, Vinca E, Ceranski K, Carreño-Gonzalez MJ, Romero-Pérez L, Wehweck FS, Musa J, Bestvater F, Knott MML, Hölting TLB, Hartmann W, Dirksen U, Kirchner T, Cidre-Aranaz F, Grünewald TGP. Ohmura S, et al. Among authors: knott mml. Mol Cancer. 2021 Jul 27;20(1):97. doi: 10.1186/s12943-021-01393-9. Mol Cancer. 2021. PMID: 34315482 Free PMC article. No abstract available.
Neomorphic DNA-binding enables tumor-specific therapeutic gene expression in fusion-addicted childhood sarcoma.
Hölting TLB, Cidre-Aranaz F, Matzek D, Popper B, Jacobi SJ, Funk CM, Geyer FH, Li J, Piseddu I, Cadilha BL, Ledderose S, Zwilling J, Ohmura S, Anz D, Künkele A, Klauschen F, Grünewald TGP, Knott MML. Hölting TLB, et al. Among authors: knott mml. Mol Cancer. 2022 Oct 13;21(1):199. doi: 10.1186/s12943-022-01641-6. Mol Cancer. 2022. PMID: 36229873 Free PMC article.
26 results