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186 results

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Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, Cho H, Erickson C, Singer M, Cui D, Tittley S, Durham BH, Pavletich TS, Fiala E, Walsh MF, Inoue D, Monette S, Taylor J, Rosen N, McCormick F, Lindsley RC, Castel P, Abdel-Wahab O. Chen S, et al. Among authors: knorr k. Cancer Discov. 2022 Oct 5;12(10):2434-2453. doi: 10.1158/2159-8290.CD-21-1631. Cancer Discov. 2022. PMID: 35904492 Free PMC article.
Single-cell genomics reveals the genetic and molecular bases for escape from mutational epistasis in myeloid neoplasms.
Taylor J, Mi X, North K, Binder M, Penson A, Lasho T, Knorr K, Haddadin M, Liu B, Pangallo J, Benbarche S, Wiseman D, Tefferi A, Halene S, Liang Y, Patnaik MM, Bradley RK, Abdel-Wahab O. Taylor J, et al. Among authors: knorr k. Blood. 2020 Sep 24;136(13):1477-1486. doi: 10.1182/blood.2020006868. Blood. 2020. PMID: 32640014 Free PMC article.
Aberrant RNA Splicing in Cancer.
Escobar-Hoyos L, Knorr K, Abdel-Wahab O. Escobar-Hoyos L, et al. Among authors: knorr k. Annu Rev Cancer Biol. 2019 Mar;3(1):167-185. doi: 10.1146/annurev-cancerbio-030617-050407. Epub 2018 Nov 28. Annu Rev Cancer Biol. 2019. PMID: 32864546 Free PMC article.
Minor intron retention drives clonal hematopoietic disorders and diverse cancer predisposition.
Inoue D, Polaski JT, Taylor J, Castel P, Chen S, Kobayashi S, Hogg SJ, Hayashi Y, Pineda JMB, El Marabti E, Erickson C, Knorr K, Fukumoto M, Yamazaki H, Tanaka A, Fukui C, Lu SX, Durham BH, Liu B, Wang E, Mehta S, Zakheim D, Garippa R, Penson A, Chew GL, McCormick F, Bradley RK, Abdel-Wahab O. Inoue D, et al. Among authors: knorr k. Nat Genet. 2021 May;53(5):707-718. doi: 10.1038/s41588-021-00828-9. Epub 2021 Apr 12. Nat Genet. 2021. PMID: 33846634 Free PMC article.
Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.
Wang E, Pineda JMB, Kim WJ, Chen S, Bourcier J, Stahl M, Hogg SJ, Bewersdorf JP, Han C, Singer ME, Cui D, Erickson CE, Tittley SM, Penson AV, Knorr K, Stanley RF, Rahman J, Krishnamoorthy G, Fagin JA, Creger E, McMillan E, Mak CC, Jarvis M, Bossard C, Beaupre DM, Bradley RK, Abdel-Wahab O. Wang E, et al. Among authors: knorr k. Cancer Cell. 2023 Jan 9;41(1):164-180.e8. doi: 10.1016/j.ccell.2022.12.002. Epub 2022 Dec 22. Cancer Cell. 2023. PMID: 36563682 Free PMC article.
Systematic evaluation of AML-associated antigens identifies anti-U5 SNRNP200 therapeutic antibodies for the treatment of acute myeloid leukemia.
Knorr K, Rahman J, Erickson C, Wang E, Monetti M, Li Z, Ortiz-Pacheco J, Jones A, Lu SX, Stanley RF, Baez M, Fox N, Castro C, Marino AE, Jiang C, Penson A, Hogg SJ, Mi X, Nakajima H, Kunimoto H, Nishimura K, Inoue D, Greenbaum B, Knorr D, Ravetch J, Abdel-Wahab O. Knorr K, et al. Nat Cancer. 2023 Dec;4(12):1675-1692. doi: 10.1038/s43018-023-00656-2. Epub 2023 Oct 23. Nat Cancer. 2023. PMID: 37872381 Free PMC article.
LeukeMYC prognostication.
Knorr KLB, Tallman MS. Knorr KLB, et al. Leuk Lymphoma. 2019 Jan;60(1):1-2. doi: 10.1080/10428194.2018.1482547. Epub 2018 Jul 6. Leuk Lymphoma. 2019. PMID: 29979098 No abstract available.
186 results