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Activation of bile salt nuclear receptor FXR is repressed by pro-inflammatory cytokines activating NF-κB signaling in the intestine.
Gadaleta RM, Oldenburg B, Willemsen EC, Spit M, Murzilli S, Salvatore L, Klomp LW, Siersema PD, van Erpecum KJ, van Mil SW. Gadaleta RM, et al. Among authors: klomp lw. Biochim Biophys Acta. 2011 Aug;1812(8):851-8. doi: 10.1016/j.bbadis.2011.04.005. Epub 2011 Apr 22. Biochim Biophys Acta. 2011. PMID: 21540105 Free article.
Genetics of familial intrahepatic cholestasis syndromes.
van Mil SW, Houwen RH, Klomp LW. van Mil SW, et al. Among authors: klomp lw. J Med Genet. 2005 Jun;42(6):449-63. doi: 10.1136/jmg.2004.026187. J Med Genet. 2005. PMID: 15937079 Free PMC article. Review.
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