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Leveraging QSP Models for MIPD: A Case Study for Warfarin/INR.
Falkenhagen U, Cavallari LH, Duarte JD, Kloft C, Schmidt S, Huisinga W. Falkenhagen U, et al. Among authors: kloft c. Clin Pharmacol Ther. 2024 Apr 24. doi: 10.1002/cpt.3274. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38655898
Nonlinear Mixed-Effects Model of Z-Endoxifen Concentrations in Tamoxifen-Treated Patients from the CEPAM Cohort.
Mc Laughlin AM, Helland T, Klima F, Koolen SLW, van Schaik RHN, Mathijssen RHJ, Neven P, Swen JJ, Guchelaar HJ, Dalenc F, White-Koning M, Michelet R, Mikus G, Schroth W, Mürdter T, Brauch H, Schwab M, Søiland H, Mellgren G, Thomas F, Kloft C, Hertz DL; CYP2D6 Endoxifen Percentage Activity Model (CEPAM) Consortium. Mc Laughlin AM, et al. Among authors: kloft c. Clin Pharmacol Ther. 2024 Mar 18. doi: 10.1002/cpt.3238. Online ahead of print. Clin Pharmacol Ther. 2024. PMID: 38494911
TLD-1, a novel liposomal doxorubicin, in patients with advanced solid tumors: Dose escalation and expansion part of a multicenter open-label phase I trial (SAKK 65/16).
Colombo I, Koster KL, Holer L, Haefliger S, Rabaglio M, Bastian S, Schwitter M, Eckhardt K, Hayoz S, Mc Laughlin AM, Kloft C, Klose M, Halbherr S, Baumgartner C, Sessa C, Stathis A, Hess D, Joerger M. Colombo I, et al. Among authors: kloft c. Eur J Cancer. 2024 Apr;201:113588. doi: 10.1016/j.ejca.2024.113588. Epub 2024 Feb 2. Eur J Cancer. 2024. PMID: 38377773 Free article. Clinical Trial.
Forecasting antimicrobial resistance evolution.
Rolff J, Bonhoeffer S, Kloft C, Leistner R, Regoes R, Hochberg ME. Rolff J, et al. Among authors: kloft c. Trends Microbiol. 2024 Jan 18:S0966-842X(23)00361-X. doi: 10.1016/j.tim.2023.12.009. Online ahead of print. Trends Microbiol. 2024. PMID: 38238231 Review.
211 results