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Genome-Wide DNA Methylation Profiling in Early Stage I Lung Adenocarcinoma Reveals Predictive Aberrant Methylation in the Promoter Region of the Long Noncoding RNA PLUT: An Exploratory Study.
Kim-Wanner SZ, Assenov Y, Nair MB, Weichenhan D, Benner A, Becker N, Landwehr K, Kuner R, Sültmann H, Esteller M, Koch I, Lindner M, Meister M, Thomas M, Bieg M, Klingmüller U, Schlesner M, Warth A, Brors B, Seifried E, Bönig H, Plass C, Risch A, Muley T. Kim-Wanner SZ, et al. Among authors: klingmuller u. J Thorac Oncol. 2020 Aug;15(8):1338-1350. doi: 10.1016/j.jtho.2020.03.023. Epub 2020 Apr 7. J Thorac Oncol. 2020. PMID: 32272161 Free article.
Hepatocytes reprogram liver macrophages involving control of TGF-β activation, influencing liver regeneration and injury.
Wolf SD, Ehlting C, Müller-Dott S, Poschmann G, Petzsch P, Lautwein T, Wang S, Helm B, Schilling M, Saez-Rodriguez J, Vucur M, Stühler K, Köhrer K, Tacke F, Dooley S, Klingmüller U, Luedde T, Bode JG. Wolf SD, et al. Among authors: klingmuller u. Hepatol Commun. 2023 Jul 24;7(8):e0208. doi: 10.1097/HC9.0000000000000208. eCollection 2023 Aug 1. Hepatol Commun. 2023. PMID: 37486964 Free PMC article.
Downregulation of the TGFβ Pseudoreceptor BAMBI in Non-Small Cell Lung Cancer Enhances TGFβ Signaling and Invasion.
Marwitz S, Depner S, Dvornikov D, Merkle R, Szczygieł M, Müller-Decker K, Lucarelli P, Wäsch M, Mairbäurl H, Rabe KF, Kugler C, Vollmer E, Reck M, Scheufele S, Kröger M, Ammerpohl O, Siebert R, Goldmann T, Klingmüller U. Marwitz S, et al. Among authors: klingmuller u. Cancer Res. 2016 Jul 1;76(13):3785-801. doi: 10.1158/0008-5472.CAN-15-1326. Epub 2016 May 17. Cancer Res. 2016. PMID: 27197161
Identification of Cell Type-Specific Differences in Erythropoietin Receptor Signaling in Primary Erythroid and Lung Cancer Cells.
Merkle R, Steiert B, Salopiata F, Depner S, Raue A, Iwamoto N, Schelker M, Hass H, Wäsch M, Böhm ME, Mücke O, Lipka DB, Plass C, Lehmann WD, Kreutz C, Timmer J, Schilling M, Klingmüller U. Merkle R, et al. Among authors: klingmuller u. PLoS Comput Biol. 2016 Aug 5;12(8):e1005049. doi: 10.1371/journal.pcbi.1005049. eCollection 2016 Aug. PLoS Comput Biol. 2016. PMID: 27494133 Free PMC article.
Expression ratio of the TGFβ-inducible gene MYO10 is prognostic for overall survival of squamous cell lung cancer patients and predicts chemotherapy response.
Dvornikov D, Schneider MA, Ohse S, Szczygieł M, Titkova I, Rosenblatt M, Muley T, Warth A, Herth FJ, Dienemann H, Thomas M, Timmer J, Schilling M, Busch H, Boerries M, Meister M, Klingmüller U. Dvornikov D, et al. Among authors: klingmuller u. Sci Rep. 2018 Jun 22;8(1):9517. doi: 10.1038/s41598-018-27912-1. Sci Rep. 2018. PMID: 29934580 Free PMC article.
Comprehensive serial biobanking in advanced NSCLC: feasibility, challenges and perspectives.
Wessels S, Muley T, Christopoulos P, Meister M, Heinzmann-Groth I, Warth A, Herpel E, Hummler S, Klingmüller U, Kuon J, Heussel CP, Eberhardt R, Herth FJF, Winter H, Bischoff H, Stenzinger A, Reck M, Huber RM, Thomas M, Schneider MA. Wessels S, et al. Among authors: klingmuller u. Transl Lung Cancer Res. 2020 Aug;9(4):1000-1014. doi: 10.21037/tlcr-20-137. Transl Lung Cancer Res. 2020. PMID: 32953480 Free PMC article.
Conditional deletion of Nedd4-2 in lung epithelial cells causes progressive pulmonary fibrosis in adult mice.
Duerr J, Leitz DHW, Szczygiel M, Dvornikov D, Fraumann SG, Kreutz C, Zadora PK, Seyhan Agircan A, Konietzke P, Engelmann TA, Hegermann J, Mulugeta S, Kawabe H, Knudsen L, Ochs M, Rotin D, Muley T, Kreuter M, Herth FJF, Wielpütz MO, Beers MF, Klingmüller U, Mall MA. Duerr J, et al. Among authors: klingmuller u. Nat Commun. 2020 Apr 24;11(1):2012. doi: 10.1038/s41467-020-15743-6. Nat Commun. 2020. PMID: 32332792 Free PMC article.
Dynamic mathematical modeling of IL13-induced signaling in Hodgkin and primary mediastinal B-cell lymphoma allows prediction of therapeutic targets.
Raia V, Schilling M, Böhm M, Hahn B, Kowarsch A, Raue A, Sticht C, Bohl S, Saile M, Möller P, Gretz N, Timmer J, Theis F, Lehmann WD, Lichter P, Klingmüller U. Raia V, et al. Among authors: klingmuller u. Cancer Res. 2011 Feb 1;71(3):693-704. doi: 10.1158/0008-5472.CAN-10-2987. Epub 2010 Dec 2. Cancer Res. 2011. PMID: 21127196
Whither systems medicine?
Apweiler R, Beissbarth T, Berthold MR, Blüthgen N, Burmeister Y, Dammann O, Deutsch A, Feuerhake F, Franke A, Hasenauer J, Hoffmann S, Höfer T, Jansen PL, Kaderali L, Klingmüller U, Koch I, Kohlbacher O, Kuepfer L, Lammert F, Maier D, Pfeifer N, Radde N, Rehm M, Roeder I, Saez-Rodriguez J, Sax U, Schmeck B, Schuppert A, Seilheimer B, Theis FJ, Vera J, Wolkenhauer O. Apweiler R, et al. Among authors: klingmuller u. Exp Mol Med. 2018 Mar 2;50(3):e453. doi: 10.1038/emm.2017.290. Exp Mol Med. 2018. PMID: 29497170 Free PMC article. Review.
133 results