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Cold-stimulated brown adipose tissue activation is related to changes in serum metabolites relevant to NAD+ metabolism in humans.
U-Din M, de Mello VD, Tuomainen M, Raiko J, Niemi T, Fromme T, Klåvus A, Gautier N, Haimilahti K, Lehtonen M, Kristiansen K, Newman JW, Pietiläinen KH, Pihlajamäki J, Amri EZ, Klingenspor M, Nuutila P, Pirinen E, Hanhineva K, Virtanen KA. U-Din M, et al. Among authors: klingenspor m. Cell Rep. 2023 Sep 26;42(9):113131. doi: 10.1016/j.celrep.2023.113131. Epub 2023 Sep 13. Cell Rep. 2023. PMID: 37708023 Free article.
High-Throughput Screening and Proteomic Characterization of Compounds Targeting Myeloid-Derived Suppressor Cells.
Krumm J, Petrova E, Lechner S, Mergner J, Boehm HH, Prestipino A, Steinbrunn D, Deline ML, Koetzner L, Schindler C, Helming L, Fromme T, Klingenspor M, Hahne H, Pieck JC, Kuster B. Krumm J, et al. Among authors: klingenspor m. Mol Cell Proteomics. 2023 Sep;22(9):100632. doi: 10.1016/j.mcpro.2023.100632. Epub 2023 Aug 14. Mol Cell Proteomics. 2023. PMID: 37586548 Free PMC article.
The negative adipogenesis regulator Dlk1 is transcriptionally regulated by Ifrd1 (TIS7) and translationally by its orthologue Ifrd2 (SKMc15).
Vietor I, Cikes D, Piironen K, Vasakou T, Heimdörfer D, Gstir R, Erlacher MD, Tancevski I, Eller P, Demetz E, Hess MW, Kuhn V, Degenhart G, Rozman J, Klingenspor M, Hrabe de Angelis M, Valovka T, Huber LA. Vietor I, et al. Among authors: klingenspor m. Elife. 2023 Aug 21;12:e88350. doi: 10.7554/eLife.88350. Elife. 2023. PMID: 37603466 Free PMC article.
Pyrimidine de novo synthesis inhibition selectively blocks effector but not memory T cell development.
Scherer S, Oberle SG, Kanev K, Gerullis AK, Wu M, de Almeida GP, Puleston DJ, Baixauli F, Aly L, Greco A, Nizharadze T, Becker NB, Hoesslin MV, Donhauser LV, Berner J, Chu T, McNamara HA, Esencan Z, Roelli P, Wurmser C, Kleiter I, Vehreschild MJGT, Mayer CA, Knolle P, Klingenspor M, Fumagalli V, Iannacone M, Prlic M, Korn T, Pearce EL, Höfer T, Schulz AM, Zehn D. Scherer S, et al. Among authors: klingenspor m. Nat Immunol. 2023 Mar;24(3):501-515. doi: 10.1038/s41590-023-01436-x. Epub 2023 Feb 16. Nat Immunol. 2023. PMID: 36797499
Effects of Fatty Acid Metabolites on Adipocytes Britening: Role of Thromboxane A2.
Colson C, Batrow PL, Dieckmann S, Contu L, Roux CH, Balas L, Vigor C, Fourmaux B, Gautier N, Rochet N, Bernoud-Hubac N, Durand T, Langin D, Klingenspor M, Amri EZ. Colson C, et al. Among authors: klingenspor m. Cells. 2023 Jan 30;12(3):446. doi: 10.3390/cells12030446. Cells. 2023. PMID: 36766790 Free PMC article.
Secretin modulates appetite via brown adipose tissue-brain axis.
Sun L, Laurila S, Lahesmaa M, Rebelos E, Virtanen KA, Schnabl K, Klingenspor M, Nummenmaa L, Nuutila P. Sun L, et al. Among authors: klingenspor m. Eur J Nucl Med Mol Imaging. 2023 May;50(6):1597-1606. doi: 10.1007/s00259-023-06124-4. Epub 2023 Feb 11. Eur J Nucl Med Mol Imaging. 2023. PMID: 36764966 Free PMC article. Clinical Trial.
Deep phenotyping and lifetime trajectories reveal limited effects of longevity regulators on the aging process in C57BL/6J mice.
Xie K, Fuchs H, Scifo E, Liu D, Aziz A, Aguilar-Pimentel JA, Amarie OV, Becker L, da Silva-Buttkus P, Calzada-Wack J, Cho YL, Deng Y, Edwards AC, Garrett L, Georgopoulou C, Gerlini R, Hölter SM, Klein-Rodewald T, Kramer M, Leuchtenberger S, Lountzi D, Mayer-Kuckuk P, Nover LL, Oestereicher MA, Overkott C, Pearson BL, Rathkolb B, Rozman J, Russ J, Schaaf K, Spielmann N, Sanz-Moreno A, Stoeger C, Treise I, Bano D, Busch DH, Graw J, Klingenspor M, Klopstock T, Mock BA, Salomoni P, Schmidt-Weber C, Weiergräber M, Wolf E, Wurst W, Gailus-Durner V, Breteler MMB, Hrabě de Angelis M, Ehninger D. Xie K, et al. Among authors: klingenspor m. Nat Commun. 2022 Nov 11;13(1):6830. doi: 10.1038/s41467-022-34515-y. Nat Commun. 2022. PMID: 36369285 Free PMC article.
238 results