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The emergency medical service has a crucial role to unravel the genetics of sudden cardiac arrest in young, out of hospital resuscitated patients: Interim data from the MAP-IT study.
Tiesmeier J, Gaertner A, Homm S, Jakob T, Stanasiuk C, Bachmann-Mennenga B, Henzler D, Grautoff S, Veit G, Hori E, Kellner U, Gummert JF, Hitz MP, Kostareva A, Klingel K, Paluszkiewicz L, Laser KT, Pfeiffer H, Fox H, Milting H. Tiesmeier J, et al. Among authors: klingel k. Resuscitation. 2021 Nov;168:176-185. doi: 10.1016/j.resuscitation.2021.07.042. Epub 2021 Aug 10. Resuscitation. 2021. PMID: 34389451 Free article.
Myocardial expression profiles of candidate molecules in patients with arrhythmogenic right ventricular cardiomyopathy/dysplasia compared to those with dilated cardiomyopathy and healthy controls.
Akdis D, Medeiros-Domingo A, Gaertner-Rommel A, Kast JI, Enseleit F, Bode P, Klingel K, Kandolf R, Renois F, Andreoletti L, Akdis CA, Milting H, Lüscher TF, Brunckhorst C, Saguner AM, Duru F. Akdis D, et al. Among authors: klingel k. Heart Rhythm. 2016 Mar;13(3):731-41. doi: 10.1016/j.hrthm.2015.11.010. Epub 2015 Nov 10. Heart Rhythm. 2016. PMID: 26569459 Free article.
Molecular autopsy and family screening in a young case of sudden cardiac death reveals an unusually severe case of FHL1 related hypertrophic cardiomyopathy.
Gaertner-Rommel A, Tiesmeier J, Jakob T, Strickmann B, Veit G, Bachmann-Mennenga B, Paluszkiewicz L, Klingel K, Schulz U, Laser KT, Karger B, Pfeiffer H, Milting H. Gaertner-Rommel A, et al. Among authors: klingel k. Mol Genet Genomic Med. 2019 Aug;7(8):e841. doi: 10.1002/mgg3.841. Epub 2019 Jul 10. Mol Genet Genomic Med. 2019. PMID: 31293105 Free PMC article.
Case Report: Early Transplant Rejection of a Methanol-Intoxicated Donor Heart in a Young Female Patient. A Diagnostic Approach With CMR, Cardiac Biopsy, and Genetic Risk Assessment.
Stoiber L, Schoenrath F, Knosalla C, Milting H, Klingel K, Tschöpe C, Tanacli R, Gebker R, Berger A, Pieske B, Kelle S. Stoiber L, et al. Among authors: klingel k. Front Immunol. 2021 Feb 22;11:575635. doi: 10.3389/fimmu.2020.575635. eCollection 2020. Front Immunol. 2021. PMID: 33692775 Free PMC article.
Hemi- and Homozygous Loss-of-Function Mutations in DSG2 (Desmoglein-2) Cause Recessive Arrhythmogenic Cardiomyopathy with an Early Onset.
Brodehl A, Meshkov A, Myasnikov R, Kiseleva A, Kulikova O, Klauke B, Sotnikova E, Stanasiuk C, Divashuk M, Pohl GM, Kudryavtseva M, Klingel K, Gerull B, Zharikova A, Gummert J, Koretskiy S, Schubert S, Mershina E, Gärtner A, Pilus P, Laser KT, Sinitsyn V, Boytsov S, Drapkina O, Milting H. Brodehl A, et al. Among authors: klingel k. Int J Mol Sci. 2021 Apr 6;22(7):3786. doi: 10.3390/ijms22073786. Int J Mol Sci. 2021. PMID: 33917638 Free PMC article.
De Novo Missense Mutations in TNNC1 and TNNI3 Causing Severe Infantile Cardiomyopathy Affect Myofilament Structure and Function and Are Modulated by Troponin Targeting Agents.
Hassoun R, Budde H, Mannherz HG, Lódi M, Fujita-Becker S, Laser KT, Gärtner A, Klingel K, Möhner D, Stehle R, Sultana I, Schaaf T, Majchrzak M, Krause V, Herrmann C, Nowaczyk MM, Mügge A, Pfitzer G, Schröder RR, Hamdani N, Milting H, Jaquet K, Cimiotti D. Hassoun R, et al. Among authors: klingel k. Int J Mol Sci. 2021 Sep 6;22(17):9625. doi: 10.3390/ijms22179625. Int J Mol Sci. 2021. PMID: 34502534 Free PMC article.
Pathogenic Variants in Cardiomyopathy Disorder Genes Underlie Pediatric Myocarditis-Further Impact of Heterozygous Immune Disorder Gene Variants?
Seidel F, Laser KT, Klingel K, Dartsch J, Theisen S, Pickardt T, Holtgrewe M, Gärtner A, Berger F, Beule D, Milting H, Schubert S, Klaassen S, Kühnisch J. Seidel F, et al. Among authors: klingel k. J Cardiovasc Dev Dis. 2022 Jul 5;9(7):216. doi: 10.3390/jcdd9070216. J Cardiovasc Dev Dis. 2022. PMID: 35877578 Free PMC article.
Spatial multi-omic map of human myocardial infarction.
Kuppe C, Ramirez Flores RO, Li Z, Hayat S, Levinson RT, Liao X, Hannani MT, Tanevski J, Wünnemann F, Nagai JS, Halder M, Schumacher D, Menzel S, Schäfer G, Hoeft K, Cheng M, Ziegler S, Zhang X, Peisker F, Kaesler N, Saritas T, Xu Y, Kassner A, Gummert J, Morshuis M, Amrute J, Veltrop RJA, Boor P, Klingel K, Van Laake LW, Vink A, Hoogenboezem RM, Bindels EMJ, Schurgers L, Sattler S, Schapiro D, Schneider RK, Lavine K, Milting H, Costa IG, Saez-Rodriguez J, Kramann R. Kuppe C, et al. Among authors: klingel k. Nature. 2022 Aug;608(7924):766-777. doi: 10.1038/s41586-022-05060-x. Epub 2022 Aug 10. Nature. 2022. PMID: 35948637 Free PMC article.
SARS-CoV-2 infects and induces cytotoxic effects in human cardiomyocytes.
Bojkova D, Wagner JUG, Shumliakivska M, Aslan GS, Saleem U, Hansen A, Luxán G, Günther S, Pham MD, Krishnan J, Harter PN, Ermel UH, Frangakis AS, Milting H, Zeiher AM, Klingel K, Cinatl J, Dendorfer A, Eschenhagen T, Tschöpe C, Ciesek S, Dimmeler S. Bojkova D, et al. Among authors: klingel k. Cardiovasc Res. 2020 Dec 1;116(14):2207-2215. doi: 10.1093/cvr/cvaa267. Cardiovasc Res. 2020. PMID: 32966582 Free PMC article.
477 results