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Targeting the mSWI/SNF Complex in POU2F-POU2AF Transcription Factor-Driven Malignancies.
He T, Xiao L, Qiao Y, Klingbeil O, Young E, Wu XS, Mannan R, Mahapatra S, Eyunni S, Tien JC, Wang X, Zheng Y, Kim N, Zheng H, Hou S, Su F, Miner SJ, Mehra R, Cao X, Sekhar AC, Samajdar S, Ramachandra M, Parolia A, Vakoc CR, Chinnaiyan AM. He T, et al. Among authors: klingbeil o. bioRxiv [Preprint]. 2024 Jan 25:2024.01.22.576669. doi: 10.1101/2024.01.22.576669. bioRxiv. 2024. PMID: 38328238 Free PMC article. Preprint.
A mucus production programme promotes classical pancreatic ductal adenocarcinoma.
Tonelli C, Yordanov GN, Hao Y, Deschênes A, Hinds J, Belleau P, Klingbeil O, Brosnan E, Doshi A, Park Y, Hruban RH, Vakoc CR, Dobin A, Preall J, Tuveson DA. Tonelli C, et al. Among authors: klingbeil o. Gut. 2024 May 10;73(6):941-954. doi: 10.1136/gutjnl-2023-329839. Gut. 2024. PMID: 38262672 Free PMC article.
BRD8 maintains glioblastoma by epigenetic reprogramming of the p53 network.
Sun X, Klingbeil O, Lu B, Wu C, Ballon C, Ouyang M, Wu XS, Jin Y, Hwangbo Y, Huang YH, Somerville TDD, Chang K, Park J, Chung T, Lyons SK, Shi J, Vogel H, Schulder M, Vakoc CR, Mills AA. Sun X, et al. Among authors: klingbeil o. Nature. 2023 Jan;613(7942):195-202. doi: 10.1038/s41586-022-05551-x. Epub 2022 Dec 21. Nature. 2023. PMID: 36544023 Free PMC article.
FoxA1 and FoxA2 control growth and cellular identity in NKX2-1-positive lung adenocarcinoma.
Orstad G, Fort G, Parnell TJ, Jones A, Stubben C, Lohman B, Gillis KL, Orellana W, Tariq R, Klingbeil O, Kaestner K, Vakoc CR, Spike BT, Snyder EL. Orstad G, et al. Among authors: klingbeil o. Dev Cell. 2022 Aug 8;57(15):1866-1882.e10. doi: 10.1016/j.devcel.2022.06.017. Epub 2022 Jul 13. Dev Cell. 2022. PMID: 35835117 Free PMC article.
Comparative optimization of combinatorial CRISPR screens.
Li R, Klingbeil O, Monducci D, Young MJ, Rodriguez DJ, Bayyat Z, Dempster JM, Kesar D, Yang X, Zamanighomi M, Vakoc CR, Ito T, Sellers WR. Li R, et al. Among authors: klingbeil o. Nat Commun. 2022 May 5;13(1):2469. doi: 10.1038/s41467-022-30196-9. Nat Commun. 2022. PMID: 35513429 Free PMC article.
SLC5A3-Dependent Myo-inositol Auxotrophy in Acute Myeloid Leukemia.
Wei Y, Huang YH, Skopelitis DS, Iyer SV, Costa ASH, Yang Z, Kramer M, Adelman ER, Klingbeil O, Demerdash OE, Polyanskaya SA, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Vakoc CR. Wei Y, et al. Among authors: klingbeil o. Cancer Discov. 2022 Feb;12(2):450-467. doi: 10.1158/2159-8290.CD-20-1849. Epub 2021 Sep 16. Cancer Discov. 2022. PMID: 34531253 Free PMC article.
Transcriptional Silencing of ALDH2 Confers a Dependency on Fanconi Anemia Proteins in Acute Myeloid Leukemia.
Yang Z, Wu XS, Wei Y, Polyanskaya SA, Iyer SV, Jung M, Lach FP, Adelman ER, Klingbeil O, Milazzo JP, Kramer M, Demerdash OE, Chang K, Goodwin S, Hodges E, McCombie WR, Figueroa ME, Smogorzewska A, Vakoc CR. Yang Z, et al. Among authors: klingbeil o. Cancer Discov. 2021 Sep;11(9):2300-2315. doi: 10.1158/2159-8290.CD-20-1542. Epub 2021 Apr 23. Cancer Discov. 2021. PMID: 33893150 Free PMC article.
17 results