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Lack of CCDC146, a ubiquitous centriole and microtubule-associated protein, leads to non-syndromic male infertility in human and mouse.
Muroňová J, Kherraf ZE, Giordani E, Lambert E, Eckert S, Cazin C, Amiri-Yekta A, Court M, Chevalier G, Martinez G, Neirijnck Y, Kühne F, Wehrli L, Klena N, Hamel V, De Macedo L, Escoffier J, Guichard P, Coutton C, Mustapha SFB, Kharouf M, Bouin AP, Zouari R, Thierry-Mieg N, Nef S, Geimer S, Loeuillet C, Ray PF, Arnoult C. Muroňová J, et al. Among authors: klena n. Elife. 2024 Mar 5;12:RP86845. doi: 10.7554/eLife.86845. Elife. 2024. PMID: 38441556 Free PMC article.
Structural Biology of Cilia and Intraflagellar Transport.
Klena N, Pigino G. Klena N, et al. Annu Rev Cell Dev Biol. 2022 Oct 6;38:103-123. doi: 10.1146/annurev-cellbio-120219-034238. Epub 2022 Jun 29. Annu Rev Cell Dev Biol. 2022. PMID: 35767872 Review.
Biliary-Atresia-Associated Mannosidase-1-Alpha-2 Gene Regulates Biliary and Ciliary Morphogenesis and Laterality.
So J, Ningappa M, Glessner J, Min J, Ashokkumar C, Ranganathan S, Higgs BW, Li D, Sun Q, Schmitt L, Biery AC, Dobrowolski S, Trautz C, Fuhrman L, Schwartz MC, Klena NT, Fusco J, Prasadan K, Adenuga M, Mohamed N, Yan Q, Chen W, Horne W, Dhawan A, Sharif K, Kelly D, Squires RH, Gittes GK, Hakonarson H, Morell V, Lo C, Subramaniam S, Shin D, Sindhi R. So J, et al. Among authors: klena nt. Front Physiol. 2020 Oct 30;11:538701. doi: 10.3389/fphys.2020.538701. eCollection 2020. Front Physiol. 2020. PMID: 33192543 Free PMC article.
Overview of the centriole architecture.
LeGuennec M, Klena N, Aeschlimann G, Hamel V, Guichard P. LeGuennec M, et al. Among authors: klena n. Curr Opin Struct Biol. 2021 Feb;66:58-65. doi: 10.1016/j.sbi.2020.09.015. Epub 2020 Nov 8. Curr Opin Struct Biol. 2021. PMID: 33176264 Free article. Review.
A helical inner scaffold provides a structural basis for centriole cohesion.
Le Guennec M, Klena N, Gambarotto D, Laporte MH, Tassin AM, van den Hoek H, Erdmann PS, Schaffer M, Kovacik L, Borgers S, Goldie KN, Stahlberg H, Bornens M, Azimzadeh J, Engel BD, Hamel V, Guichard P. Le Guennec M, et al. Among authors: klena n. Sci Adv. 2020 Feb 14;6(7):eaaz4137. doi: 10.1126/sciadv.aaz4137. eCollection 2020 Feb. Sci Adv. 2020. PMID: 32110738 Free PMC article.
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