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Periostin- and podoplanin-positive cancer-associated fibroblast subtypes cooperate to shape the inflamed tumor microenvironment in aggressive pancreatic adenocarcinoma.
Neuzillet C, Nicolle R, Raffenne J, Tijeras-Raballand A, Brunel A, Astorgues-Xerri L, Vacher S, Arbateraz F, Fanjul M, Hilmi M, Samain R, Klein C, Perraud A, Rebours V, Mathonnet M, Bièche I, Kocher H, Cros J, Bousquet C. Neuzillet C, et al. Among authors: klein c. J Pathol. 2022 Dec;258(4):408-425. doi: 10.1002/path.6011. Epub 2022 Oct 21. J Pathol. 2022. PMID: 36102377 Free PMC article.
Human adipocyte function is impacted by mechanical cues.
Pellegrinelli V, Heuvingh J, du Roure O, Rouault C, Devulder A, Klein C, Lacasa M, Clément E, Lacasa D, Clément K. Pellegrinelli V, et al. Among authors: klein c. J Pathol. 2014 Jun;233(2):183-95. doi: 10.1002/path.4347. J Pathol. 2014. PMID: 24623048
Metabolic enzymes expressed by cancer cells impact the immune infiltrate.
Stoll G, Kremer M, Bloy N, Joseph A, Castedo M, Meurice G, Klein C, Galluzzi L, Michels J, Kroemer G. Stoll G, et al. Among authors: klein c. Oncoimmunology. 2019 Mar 30;8(6):e1571389. doi: 10.1080/2162402X.2019.1571389. eCollection 2019. Oncoimmunology. 2019. PMID: 31069148 Free PMC article.
Metabolic features of cancer cells impact immunosurveillance.
Joseph A, Juncheng P, Mondini M, Labaied N, Loi M, Adam J, Lafarge A, Astesana V, Obrist F, Klein C, Bloy N, Stoll G, Signolle N, Genestie C, Damotte D, Alifano M, Leary A, Pautier P, Morice P, Gouy S, Deutsch E, Chargari C, Dieu-Nosjean MC, Cremer I, Michels J, Kroemer G, Castedo M. Joseph A, et al. Among authors: klein c. J Immunother Cancer. 2021 Jun;9(6):e002362. doi: 10.1136/jitc-2021-002362. J Immunother Cancer. 2021. PMID: 34162714 Free PMC article.
Artificial intelligence predicts immune and inflammatory gene signatures directly from hepatocellular carcinoma histology.
Zeng Q, Klein C, Caruso S, Maille P, Laleh NG, Sommacale D, Laurent A, Amaddeo G, Gentien D, Rapinat A, Regnault H, Charpy C, Nguyen CT, Tournigand C, Brustia R, Pawlotsky JM, Kather JN, Maiuri MC, Loménie N, Calderaro J. Zeng Q, et al. Among authors: klein c. J Hepatol. 2022 Jul;77(1):116-127. doi: 10.1016/j.jhep.2022.01.018. Epub 2022 Feb 7. J Hepatol. 2022. PMID: 35143898
Polyploidy spectrum: a new marker in HCC classification.
Bou-Nader M, Caruso S, Donne R, Celton-Morizur S, Calderaro J, Gentric G, Cadoux M, L'Hermitte A, Klein C, Guilbert T, Albuquerque M, Couchy G, Paradis V, Couty JP, Zucman-Rossi J, Desdouets C. Bou-Nader M, et al. Among authors: klein c. Gut. 2020 Feb;69(2):355-364. doi: 10.1136/gutjnl-2018-318021. Epub 2019 Apr 12. Gut. 2020. PMID: 30979717 Free PMC article.
Dendritic cells in tumor-associated tertiary lymphoid structures signal a Th1 cytotoxic immune contexture and license the positive prognostic value of infiltrating CD8+ T cells.
Goc J, Germain C, Vo-Bourgais TK, Lupo A, Klein C, Knockaert S, de Chaisemartin L, Ouakrim H, Becht E, Alifano M, Validire P, Remark R, Hammond SA, Cremer I, Damotte D, Fridman WH, Sautès-Fridman C, Dieu-Nosjean MC. Goc J, et al. Among authors: klein c. Cancer Res. 2014 Feb 1;74(3):705-15. doi: 10.1158/0008-5472.CAN-13-1342. Epub 2013 Dec 23. Cancer Res. 2014. PMID: 24366885
Chemotherapy-induced ileal crypt apoptosis and the ileal microbiome shape immunosurveillance and prognosis of proximal colon cancer.
Roberti MP, Yonekura S, Duong CPM, Picard M, Ferrere G, Tidjani Alou M, Rauber C, Iebba V, Lehmann CHK, Amon L, Dudziak D, Derosa L, Routy B, Flament C, Richard C, Daillère R, Fluckiger A, Van Seuningen I, Chamaillard M, Vincent A, Kourula S, Opolon P, Ly P, Pizzato E, Becharef S, Paillet J, Klein C, Marliot F, Pietrantonio F, Benoist S, Scoazec JY, Dartigues P, Hollebecque A, Malka D, Pagès F, Galon J, Gomperts Boneca I, Lepage P, Ryffel B, Raoult D, Eggermont A, Vanden Berghe T, Ghiringhelli F, Vandenabeele P, Kroemer G, Zitvogel L. Roberti MP, et al. Among authors: klein c. Nat Med. 2020 Jun;26(6):919-931. doi: 10.1038/s41591-020-0882-8. Epub 2020 May 25. Nat Med. 2020. PMID: 32451498 Free article.
Spatial profiling of ovarian carcinoma and tumor microenvironment evolution under neoadjuvant chemotherapy.
Yaniz-Galende E, Zeng Q, Grau-Bejar JF, Klein C, Blanc-Durand F, Le Formal A, Pujade-Lauraine E, Chardin L, Edmond E, Marty V, Ray-Coquard I, Joly F, Ferron G, Pautier P, Berton-Rigaud D, Lortholary A, Dohollou N, Desauw C, Fabbro M, Malaurie E, Bonichon-Lamichhane N, Bello Roufai D, Gantzer J, Rouleau E, Genestie C, Leary A. Yaniz-Galende E, et al. Among authors: klein c. Clin Cancer Res. 2024 Apr 26. doi: 10.1158/1078-0432.CCR-23-3836. Online ahead of print. Clin Cancer Res. 2024. PMID: 38669064
3,906 results