Kleczko EK - Search Results

1

Inflammation promotes aging-associated oncogenesis in the lung.

Pham-Danis C, Chia SB, Scarborough HA, Danis E, Nemkov T, Kleczko EK, Navarro A, Goodspeed A, Bonney EA, Dinarello CA, Marchetti C, Nemenoff RA, Hansen K, DeGregori J. Pham-Danis C, et al. Among authors: kleczko ek. bioRxiv [Preprint]. 2024 Mar 5:2024.03.01.583044. doi: 10.1101/2024.03.01.583044. bioRxiv. 2024. PMID: 38496448 Free PMC article. Preprint.

2

Immune checkpoint activity regulates polycystic kidney disease progression.

Kleczko EK, Nguyen DT, Marsh KH, Bauer CD, Li AS, Monaghan MT, Berger MD, Furgeson SB, Gitomer BY, Chonchol MB, Clambey ET, Zimmerman KA, Nemenoff RA, Hopp K. Kleczko EK, et al. JCI Insight. 2023 Jun 22;8(12):e161318. doi: 10.1172/jci.insight.161318. JCI Insight. 2023. PMID: 37345660 Free PMC article.

3

Evaluation of KRAS^G12C inhibitor responses in novel murine KRAS^G12C lung cancer cell line models.

Sisler DJ, Hinz TK, Le AT, Kleczko EK, Nemenoff RA, Heasley LE. Sisler DJ, et al. Among authors: kleczko ek. Front Oncol. 2023 Feb 8;13:1094123. doi: 10.3389/fonc.2023.1094123. eCollection 2023. Front Oncol. 2023. PMID: 36845684 Free PMC article.

4

Durable responses to alectinib in murine models of EML4-ALK lung cancer requires adaptive immunity.

Kleczko EK, Hinz TK, Nguyen TT, Gurule NJ, Navarro A, Le AT, Johnson AM, Kwak J, Polhac DI, Clambey ET, Weiser-Evans M, Merrick DT, Yang MC, Patil T, Schenk EL, Heasley LE, Nemenoff RA. Kleczko EK, et al. NPJ Precis Oncol. 2023 Feb 4;7(1):15. doi: 10.1038/s41698-023-00355-2. NPJ Precis Oncol. 2023. PMID: 36739466 Free PMC article.

5

Upregulation of complement proteins in lung cancer cells mediates tumor progression.

Kleczko EK, Poczobutt JM, Navarro AC, Laskowski J, Johnson AM, Korpela SP, Gurule NJ, Heasley LE, Hopp K, Weiser-Evans MCM, Gottlin EB, Bushey RT, Campa MJ, Patz EF Jr, Thurman JM, Nemenoff RA. Kleczko EK, et al. Front Oncol. 2023 Jan 5;12:1045690. doi: 10.3389/fonc.2022.1045690. eCollection 2022. Front Oncol. 2023. PMID: 36686777 Free PMC article.

6

Novel EGFR-mutant mouse models of lung adenocarcinoma reveal adaptive immunity requirement for durable osimertinib response.

Kleczko EK, Le AT, Hinz TK, Nguyen TT, Navarro A, Hu CJ, Selman AM, Clambey ET, Merrick DT, Lu S, Weiser-Evans M, Nemenoff RA, Heasley LE. Kleczko EK, et al. Cancer Lett. 2023 Mar 1;556:216062. doi: 10.1016/j.canlet.2023.216062. Epub 2023 Jan 16. Cancer Lett. 2023. PMID: 36657561 Free PMC article.

7

The tryptophan-metabolizing enzyme indoleamine 2,3-dioxygenase 1 regulates polycystic kidney disease progression.

Nguyen DT, Kleczko EK, Dwivedi N, Monaghan MT, Gitomer BY, Chonchol MB, Clambey ET, Nemenoff RA, Klawitter J, Hopp K. Nguyen DT, et al. Among authors: kleczko ek. JCI Insight. 2023 Jan 10;8(1):e154773. doi: 10.1172/jci.insight.154773. JCI Insight. 2023. PMID: 36422996 Free PMC article.

8

Metabolic reprogramming in a slowly developing orthologous model of polycystic kidney disease.

Hopp K, Kleczko EK, Gitomer BY, Chonchol M, Klawitter J, Christians U, Klawitter J. Hopp K, et al. Among authors: kleczko ek. Am J Physiol Renal Physiol. 2022 Mar 1;322(3):F258-F267. doi: 10.1152/ajprenal.00262.2021. Epub 2022 Jan 17. Am J Physiol Renal Physiol. 2022. PMID: 35037466 Free PMC article.

9

Complement C3a and C5a receptor blockade modulates regulatory T cell conversion in head and neck cancer.

Gadwa J, Bickett TE, Darragh LB, Knitz MW, Bhatia S, Piper M, Van Court B, Bhuvane S, Nguyen D, Nangia V, Kleczko EK, Nemenoff RA, Karam SD. Gadwa J, et al. Among authors: kleczko ek. J Immunother Cancer. 2021 Mar;9(3):e002585. doi: 10.1136/jitc-2021-002585. J Immunother Cancer. 2021. PMID: 33789881 Free PMC article.

10

Eicosanoids in Cancer: New Roles in Immunoregulation.

Johnson AM, Kleczko EK, Nemenoff RA. Johnson AM, et al. Among authors: kleczko ek. Front Pharmacol. 2020 Nov 18;11:595498. doi: 10.3389/fphar.2020.595498. eCollection 2020. Front Pharmacol. 2020. PMID: 33364964 Free PMC article. Review.

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