Kiyatkin A - Search Results

1

Glioblastoma mutations alter EGFR dimer structure to prevent ligand bias.

Hu C, Leche CA 2nd, Kiyatkin A, Yu Z, Stayrook SE, Ferguson KM, Lemmon MA. Hu C, et al. Among authors: kiyatkin a. Nature. 2022 Feb;602(7897):518-522. doi: 10.1038/s41586-021-04393-3. Epub 2022 Feb 9. Nature. 2022. PMID: 35140400 Free PMC article.

2

Kinetics of receptor tyrosine kinase activation define ERK signaling dynamics.

Kiyatkin A, van Alderwerelt van Rosenburgh IK, Klein DE, Lemmon MA. Kiyatkin A, et al. Sci Signal. 2020 Aug 18;13(645):eaaz5267. doi: 10.1126/scisignal.aaz5267. Sci Signal. 2020. PMID: 32817373 Free PMC article.

3

EGFR Ligands Differentially Stabilize Receptor Dimers to Specify Signaling Kinetics.

Freed DM, Bessman NJ, Kiyatkin A, Salazar-Cavazos E, Byrne PO, Moore JO, Valley CC, Ferguson KM, Leahy DJ, Lidke DS, Lemmon MA. Freed DM, et al. Among authors: kiyatkin a. Cell. 2017 Oct 19;171(3):683-695.e18. doi: 10.1016/j.cell.2017.09.017. Epub 2017 Oct 5. Cell. 2017. PMID: 28988771 Free PMC article.

4

Comparison of tyrosine kinase domain properties for the neurotrophin receptors TrkA and TrkB.

Artim SC, Kiyatkin A, Lemmon MA. Artim SC, et al. Among authors: kiyatkin a. Biochem J. 2020 Oct 30;477(20):4053-4070. doi: 10.1042/BCJ20200695. Biochem J. 2020. PMID: 33043964 Free PMC article.

5

The Dark Side of Cell Signaling: Positive Roles for Negative Regulators.

Lemmon MA, Freed DM, Schlessinger J, Kiyatkin A. Lemmon MA, et al. Among authors: kiyatkin a. Cell. 2016 Mar 10;164(6):1172-1184. doi: 10.1016/j.cell.2016.02.047. Cell. 2016. PMID: 26967284 Free PMC article. Review.

6

Silence on the relevant literature and errors in implementation.

Bastiaens P, Birtwistle MR, Blüthgen N, Bruggeman FJ, Cho KH, Cosentino C, de la Fuente A, Hoek JB, Kiyatkin A, Klamt S, Kolch W, Legewie S, Mendes P, Naka T, Santra T, Sontag E, Westerhoff HV, Kholodenko BN. Bastiaens P, et al. Among authors: kiyatkin a. Nat Biotechnol. 2015 Apr;33(4):336-9. doi: 10.1038/nbt.3185. Nat Biotechnol. 2015. PMID: 25850052 No abstract available.

7

Modeling of Receptor Tyrosine Kinase Signaling: Computational and Experimental Protocols.

Fey D, Aksamitiene E, Kiyatkin A, Kholodenko BN. Fey D, et al. Among authors: kiyatkin a. Methods Mol Biol. 2017;1636:417-453. doi: 10.1007/978-1-4939-7154-1_27. Methods Mol Biol. 2017. PMID: 28730495

8

Bistability in the Rac1, PAK, and RhoA Signaling Network Drives Actin Cytoskeleton Dynamics and Cell Motility Switches.

Byrne KM, Monsefi N, Dawson JC, Degasperi A, Bukowski-Wills JC, Volinsky N, Dobrzyński M, Birtwistle MR, Tsyganov MA, Kiyatkin A, Kida K, Finch AJ, Carragher NO, Kolch W, Nguyen LK, von Kriegsheim A, Kholodenko BN. Byrne KM, et al. Among authors: kiyatkin a. Cell Syst. 2016 Jan 27;2(1):38-48. doi: 10.1016/j.cels.2016.01.003. Epub 2016 Jan 27. Cell Syst. 2016. PMID: 27136688 Free PMC article.

9

PI3K/Akt-sensitive MEK-independent compensatory circuit of ERK activation in ER-positive PI3K-mutant T47D breast cancer cells.

Aksamitiene E, Kholodenko BN, Kolch W, Hoek JB, Kiyatkin A. Aksamitiene E, et al. Among authors: kiyatkin a. Cell Signal. 2010 Sep;22(9):1369-78. doi: 10.1016/j.cellsig.2010.05.006. Epub 2010 May 12. Cell Signal. 2010. PMID: 20471474 Free PMC article.

10

Untangling the wires: a strategy to trace functional interactions in signaling and gene networks.

Kholodenko BN, Kiyatkin A, Bruggeman FJ, Sontag E, Westerhoff HV, Hoek JB. Kholodenko BN, et al. Among authors: kiyatkin a. Proc Natl Acad Sci U S A. 2002 Oct 1;99(20):12841-6. doi: 10.1073/pnas.192442699. Epub 2002 Sep 19. Proc Natl Acad Sci U S A. 2002. PMID: 12242336 Free PMC article.

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