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The histone methyltransferase DOT1L is required for proper DNA damage response, DNA repair, and modulates chemotherapy responsiveness.
Kari V, Raul SK, Henck JM, Kitz J, Kramer F, Kosinsky RL, Übelmesser N, Mansour WY, Eggert J, Spitzner M, Najafova Z, Bastians H, Grade M, Gaedcke J, Wegwitz F, Johnsen SA. Kari V, et al. Among authors: kitz j. Clin Epigenetics. 2019 Jan 7;11(1):4. doi: 10.1186/s13148-018-0601-1. Clin Epigenetics. 2019. PMID: 30616689 Free PMC article.
Frequency of HER-2 positivity in rectal cancer and prognosis.
Conradi LC, Styczen H, Sprenger T, Wolff HA, Rödel C, Nietert M, Homayounfar K, Gaedcke J, Kitz J, Talaulicar R, Becker H, Ghadimi M, Middel P, Beissbarth T, Rüschoff J, Liersch T. Conradi LC, et al. Among authors: kitz j. Am J Surg Pathol. 2013 Apr;37(4):522-31. doi: 10.1097/PAS.0b013e318272ff4d. Am J Surg Pathol. 2013. PMID: 23282976 Clinical Trial.
Identification of a microRNA expression signature for chemoradiosensitivity of colorectal cancer cells, involving miRNAs-320a, -224, -132 and let7g.
Salendo J, Spitzner M, Kramer F, Zhang X, Jo P, Wolff HA, Kitz J, Kaulfuß S, Beißbarth T, Dobbelstein M, Ghadimi M, Grade M, Gaedcke J. Salendo J, et al. Among authors: kitz j. Radiother Oncol. 2013 Sep;108(3):451-7. doi: 10.1016/j.radonc.2013.06.032. Epub 2013 Aug 7. Radiother Oncol. 2013. PMID: 23932154
STAT3 inhibition sensitizes colorectal cancer to chemoradiotherapy in vitro and in vivo.
Spitzner M, Roesler B, Bielfeld C, Emons G, Gaedcke J, Wolff HA, Rave-Fränk M, Kramer F, Beissbarth T, Kitz J, Wienands J, Ghadimi BM, Ebner R, Ried T, Grade M. Spitzner M, et al. Among authors: kitz j. Int J Cancer. 2014 Feb 15;134(4):997-1007. doi: 10.1002/ijc.28429. Epub 2013 Sep 3. Int J Cancer. 2014. PMID: 23934972 Free PMC article.
Heterogeneity of KRAS Mutation Status in Rectal Cancer.
Jo P, König A, Schirmer M, Kitz J, Conradi LC, Azizian A, Bernhardt M, Wolff HA, Grade M, Ghadimi M, Ströbel P, Schildhaus HU, Gaedcke J. Jo P, et al. Among authors: kitz j. PLoS One. 2016 Apr 11;11(4):e0153278. doi: 10.1371/journal.pone.0153278. eCollection 2016. PLoS One. 2016. PMID: 27064574 Free PMC article.
Prognostic Value of MicroRNAs in Preoperative Treated Rectal Cancer.
Azizian A, Epping I, Kramer F, Jo P, Bernhardt M, Kitz J, Salinas G, Wolff HA, Grade M, Beißbarth T, Ghadimi BM, Gaedcke J. Azizian A, et al. Among authors: kitz j. Int J Mol Sci. 2016 Apr 15;17(4):568. doi: 10.3390/ijms17040568. Int J Mol Sci. 2016. PMID: 27092493 Free PMC article.
Neoadjuvant Therapy in Rectal Cancer - Biobanking of Preoperative Tumor Biopsies.
Jo P, Nietert M, Gusky L, Kitz J, Conradi LC, Müller-Dornieden A, Schüler P, Wolff HA, Rüschoff J, Ströbel P, Grade M, Liersch T, Beißbarth T, Ghadimi MB, Sax U, Gaedcke J. Jo P, et al. Among authors: kitz j. Sci Rep. 2016 Oct 18;6:35589. doi: 10.1038/srep35589. Sci Rep. 2016. PMID: 27752113 Free PMC article.
Context-Dependent Epigenetic Regulation of Nuclear Factor of Activated T Cells 1 in Pancreatic Plasticity.
Chen NM, Neesse A, Dyck ML, Steuber B, Koenig AO, Lubeseder-Martellato C, Winter T, Forster T, Bohnenberger H, Kitz J, Reuter-Jessen K, Griesmann H, Gaedcke J, Grade M, Zhang JS, Tsai WC, Siveke J, Schildhaus HU, Ströbel P, Johnsen SA, Ellenrieder V, Hessmann E. Chen NM, et al. Among authors: kitz j. Gastroenterology. 2017 May;152(6):1507-1520.e15. doi: 10.1053/j.gastro.2017.01.043. Epub 2017 Feb 8. Gastroenterology. 2017. PMID: 28188746 Free article.
65 results