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PECAM-1 directed re-targeting of exogenous mRNA providing two orders of magnitude enhancement of vascular delivery and expression in lungs independent of apolipoprotein E-mediated uptake.
Parhiz H, Shuvaev VV, Pardi N, Khoshnejad M, Kiseleva RY, Brenner JS, Uhler T, Tuyishime S, Mui BL, Tam YK, Madden TD, Hope MJ, Weissman D, Muzykantov VR. Parhiz H, et al. Among authors: kiseleva ry. J Control Release. 2018 Dec 10;291:106-115. doi: 10.1016/j.jconrel.2018.10.015. Epub 2018 Oct 15. J Control Release. 2018. PMID: 30336167 Free PMC article.
Mechanisms that determine nanocarrier targeting to healthy versus inflamed lung regions.
Brenner JS, Bhamidipati K, Glassman PM, Ramakrishnan N, Jiang D, Paris AJ, Myerson JW, Pan DC, Shuvaev VV, Villa CH, Hood ED, Kiseleva R, Greineder CF, Radhakrishnan R, Muzykantov VR. Brenner JS, et al. Nanomedicine. 2017 May;13(4):1495-1506. doi: 10.1016/j.nano.2016.12.019. Epub 2017 Jan 5. Nanomedicine. 2017. PMID: 28065731 Free PMC article.
Targeting therapeutics to endothelium: are we there yet?
Kiseleva RY, Glassman PM, Greineder CF, Hood ED, Shuvaev VV, Muzykantov VR. Kiseleva RY, et al. Drug Deliv Transl Res. 2018 Aug;8(4):883-902. doi: 10.1007/s13346-017-0464-6. Drug Deliv Transl Res. 2018. PMID: 29282646 Free PMC article. Review.
Flexible Nanoparticles Reach Sterically Obscured Endothelial Targets Inaccessible to Rigid Nanoparticles.
Myerson JW, Braender B, Mcpherson O, Glassman PM, Kiseleva RY, Shuvaev VV, Marcos-Contreras O, Grady ME, Lee HS, Greineder CF, Stan RV, Composto RJ, Eckmann DM, Muzykantov VR. Myerson JW, et al. Among authors: kiseleva ry. Adv Mater. 2018 Aug;30(32):e1802373. doi: 10.1002/adma.201802373. Epub 2018 Jun 28. Adv Mater. 2018. PMID: 29956381 Free PMC article.
Red blood cell-hitchhiking boosts delivery of nanocarriers to chosen organs by orders of magnitude.
Brenner JS, Pan DC, Myerson JW, Marcos-Contreras OA, Villa CH, Patel P, Hekierski H, Chatterjee S, Tao JQ, Parhiz H, Bhamidipati K, Uhler TG, Hood ED, Kiseleva RY, Shuvaev VS, Shuvaeva T, Khoshnejad M, Johnston I, Gregory JV, Lahann J, Wang T, Cantu E, Armstead WM, Mitragotri S, Muzykantov V. Brenner JS, et al. Among authors: kiseleva ry. Nat Commun. 2018 Jul 11;9(1):2684. doi: 10.1038/s41467-018-05079-7. Nat Commun. 2018. PMID: 29992966 Free PMC article.
24 results