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ISG15 blocks cardiac glycolysis and ensures sufficient mitochondrial energy production during Coxsackievirus B3 infection.
Bredow C, Thery F, Wirth EK, Ochs S, Kespohl M, Kleinau G, Kelm N, Gimber N, Schmoranzer J, Voss M, Klingel K, Spranger J, Renko K, Ralser M, Mülleder M, Heuser A, Knobeloch KP, Scheerer P, Kirwan J, Brüning U, Berndt N, Impens F, Beling A. Bredow C, et al. Among authors: kirwan j. Cardiovasc Res. 2024 May 7;120(6):644-657. doi: 10.1093/cvr/cvae026. Cardiovasc Res. 2024. PMID: 38309955 Free PMC article.
Clinically used broad-spectrum antibiotics compromise inflammatory monocyte-dependent antibacterial defense in the lung.
Dörner PJ, Anandakumar H, Röwekamp I, Fiocca Vernengo F, Millet Pascual-Leone B, Krzanowski M, Sellmaier J, Brüning U, Fritsche-Guenther R, Pfannkuch L, Kurth F, Milek M, Igbokwe V, Löber U, Gutbier B, Holstein M, Heinz GA, Mashreghi MF, Schulte LN, Klatt AB, Caesar S, Wienhold SM, Offermanns S, Mack M, Witzenrath M, Jordan S, Beule D, Kirwan JA, Forslund SK, Wilck N, Bartolomaeus H, Heimesaat MM, Opitz B. Dörner PJ, et al. Among authors: kirwan ja. Nat Commun. 2024 Mar 30;15(1):2788. doi: 10.1038/s41467-024-47149-z. Nat Commun. 2024. PMID: 38555356 Free PMC article.
Exercise blood-drop metabolic profiling links metabolism with perceived exertion.
Opialla T, Gollasch B, Kuich PHJL, Klug L, Rahn G, Busjahn A, Spuler S, Boschmann M, Kirwan JA, Luft FC, Kempa S. Opialla T, et al. Among authors: kirwan ja. Front Mol Biosci. 2022 Dec 21;9:1042231. doi: 10.3389/fmolb.2022.1042231. eCollection 2022. Front Mol Biosci. 2022. PMID: 36619172 Free PMC article.
A study protocol to characterise pathophysiological and molecular markers of rheumatic heart disease and degenerative aortic stenosis using multiparametric cardiovascular imaging and multiomics techniques.
Mutithu DW, Aremu OO, Mokaila D, Bana T, Familusi M, Taylor L, Martin LJ, Heathfield LJ, Kirwan JA, Wiesner L, Adeola HA, Lumngwena EN, Manganyi R, Skatulla S, Naidoo R, Ntusi NAB. Mutithu DW, et al. Among authors: kirwan ja. PLoS One. 2024 May 13;19(5):e0303496. doi: 10.1371/journal.pone.0303496. eCollection 2024. PLoS One. 2024. PMID: 38739622
Exploratory physiological experiments are not clinical trials.
Richter EA, James DE, Kirwan JP, Zierath JR. Richter EA, et al. Among authors: kirwan jp. Cell Metab. 2024 May 7;36(5):882-883. doi: 10.1016/j.cmet.2024.04.005. Epub 2024 Apr 25. Cell Metab. 2024. PMID: 38670105 No abstract available.
875 results