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Mode of administration influences plasma levels of active Centella asiatica compounds in 5xFAD mice while markers of neuroinflammation remain unaltered.
Speers AB, Wright KM, Brandes MS, Kedjejian N, Matthews DG, Caruso M, Harris CJ, Koike S, Nguyen T, Quinn JF, Soumyanath A, Gray NE. Speers AB, et al. Among authors: wright km. Front Neurosci. 2024 Mar 25;18:1277626. doi: 10.3389/fnins.2024.1277626. eCollection 2024. Front Neurosci. 2024. PMID: 38591068 Free PMC article.
Bioanalytical method validation and application to a phase 1, double-blind, randomized pharmacokinetic trial of a standardized Centella asiatica (L.) Urban water extract product in healthy older adults.
Wright KM, Bollen M, David J, Mepham B, Alcázar Magaña A, McClure C, Maier CS, Quinn JF, Soumyanath A. Wright KM, et al. Front Pharmacol. 2023 Aug 23;14:1228030. doi: 10.3389/fphar.2023.1228030. eCollection 2023. Front Pharmacol. 2023. PMID: 37680716 Free PMC article.
Pharmacokinetics and Pharmacodynamics of Key Components of a Standardized Centella asiatica Product in Cognitively Impaired Older Adults: A Phase 1, Double-Blind, Randomized Clinical Trial.
Wright KM, Bollen M, David J, Speers AB, Brandes MS, Gray NE, Alcázar Magaña A, McClure C, Stevens JF, Maier CS, Quinn JF, Soumyanath A. Wright KM, et al. Antioxidants (Basel). 2022 Jan 23;11(2):215. doi: 10.3390/antiox11020215. Antioxidants (Basel). 2022. PMID: 35204098 Free PMC article.
Centella asiatica Alters Metabolic Pathways Associated With Alzheimer's Disease in the 5xFAD Mouse Model of ß-Amyloid Accumulation.
Speers AB, García-Jaramillo M, Feryn A, Matthews DG, Lichtenberg T, Caruso M, Wright KM, Quinn JF, Stevens JF, Maier CS, Soumyanath A, Gray NE. Speers AB, et al. Among authors: wright km. Front Pharmacol. 2021 Dec 16;12:788312. doi: 10.3389/fphar.2021.788312. eCollection 2021. Front Pharmacol. 2021. PMID: 34975484 Free PMC article.
18 results