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Dietary methionine influences therapy in mouse cancer models and alters human metabolism.
Gao X, Sanderson SM, Dai Z, Reid MA, Cooper DE, Lu M, Richie JP Jr, Ciccarella A, Calcagnotto A, Mikhael PG, Mentch SJ, Liu J, Ables G, Kirsch DG, Hsu DS, Nichenametla SN, Locasale JW. Gao X, et al. Among authors: kirsch dg. Nature. 2019 Aug;572(7769):397-401. doi: 10.1038/s41586-019-1437-3. Epub 2019 Jul 31. Nature. 2019. PMID: 31367041 Free PMC article.
Restoration of p53 function leads to tumour regression in vivo.
Ventura A, Kirsch DG, McLaughlin ME, Tuveson DA, Grimm J, Lintault L, Newman J, Reczek EE, Weissleder R, Jacks T. Ventura A, et al. Among authors: kirsch dg. Nature. 2007 Feb 8;445(7128):661-5. doi: 10.1038/nature05541. Epub 2007 Jan 24. Nature. 2007. PMID: 17251932
A spatially and temporally restricted mouse model of soft tissue sarcoma.
Kirsch DG, Dinulescu DM, Miller JB, Grimm J, Santiago PM, Young NP, Nielsen GP, Quade BJ, Chaber CJ, Schultz CP, Takeuchi O, Bronson RT, Crowley D, Korsmeyer SJ, Yoon SS, Hornicek FJ, Weissleder R, Jacks T. Kirsch DG, et al. Nat Med. 2007 Aug;13(8):992-7. doi: 10.1038/nm1602. Epub 2007 Aug 5. Nat Med. 2007. PMID: 17676052
Generation and comparison of CRISPR-Cas9 and Cre-mediated genetically engineered mouse models of sarcoma.
Huang J, Chen M, Whitley MJ, Kuo HC, Xu ES, Walens A, Mowery YM, Van Mater D, Eward WC, Cardona DM, Luo L, Ma Y, Lopez OM, Nelson CE, Robinson-Hamm JN, Reddy A, Dave SS, Gersbach CA, Dodd RD, Kirsch DG. Huang J, et al. Among authors: kirsch dg. Nat Commun. 2017 Jul 10;8:15999. doi: 10.1038/ncomms15999. Nat Commun. 2017. PMID: 28691711 Free PMC article.
Acetate Production from Glucose and Coupling to Mitochondrial Metabolism in Mammals.
Liu X, Cooper DE, Cluntun AA, Warmoes MO, Zhao S, Reid MA, Liu J, Lund PJ, Lopes M, Garcia BA, Wellen KE, Kirsch DG, Locasale JW. Liu X, et al. Among authors: kirsch dg. Cell. 2018 Oct 4;175(2):502-513.e13. doi: 10.1016/j.cell.2018.08.040. Epub 2018 Sep 20. Cell. 2018. PMID: 30245009 Free PMC article.
Neutrophils promote tumor resistance to radiation therapy.
Wisdom AJ, Hong CS, Lin AJ, Xiang Y, Cooper DE, Zhang J, Xu ES, Kuo HC, Mowery YM, Carpenter DJ, Kadakia KT, Himes JE, Luo L, Ma Y, Williams N, Cardona DM, Haldar M, Diao Y, Markovina S, Schwarz JK, Kirsch DG. Wisdom AJ, et al. Among authors: kirsch dg. Proc Natl Acad Sci U S A. 2019 Sep 10;116(37):18584-18589. doi: 10.1073/pnas.1901562116. Epub 2019 Aug 28. Proc Natl Acad Sci U S A. 2019. PMID: 31462499 Free PMC article.
272 results