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Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R; Alzheimer's Disease Neuroimaging Initiative (ADNI); Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE. Prokopenko D, et al. Among authors: kirchner r. Alzheimers Dement. 2021 Sep;17(9):1509-1527. doi: 10.1002/alz.12319. Epub 2021 Apr 2. Alzheimers Dement. 2021. PMID: 33797837 Free PMC article.
Aβ-accelerated neurodegeneration caused by Alzheimer's-associated ACE variant R1279Q is rescued by angiotensin system inhibition in mice.
Cuddy LK, Prokopenko D, Cunningham EP, Brimberry R, Song P, Kirchner R, Chapman BA, Hofmann O, Hide W, Procissi D, Hanania T, Leiser SC, Tanzi RE, Vassar R. Cuddy LK, et al. Among authors: kirchner r. Sci Transl Med. 2020 Sep 30;12(563):eaaz2541. doi: 10.1126/scitranslmed.aaz2541. Sci Transl Med. 2020. PMID: 32998969
Whole-genome sequencing reveals new Alzheimer's disease-associated rare variants in loci related to synaptic function and neuronal development.
Prokopenko D, Morgan SL, Mullin K, Hofmann O, Chapman B, Kirchner R, Amberkar S, Wohlers I, Lange C, Hide W, Bertram L, Tanzi RE. Prokopenko D, et al. Among authors: kirchner r. medRxiv [Preprint]. 2020 Nov 4:2020.11.03.20225540. doi: 10.1101/2020.11.03.20225540. medRxiv. 2020. PMID: 33173892 Free PMC article. Updated. Preprint.
166 results