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Autophagy promotes immune evasion of pancreatic cancer by degrading MHC-I.
Yamamoto K, Venida A, Yano J, Biancur DE, Kakiuchi M, Gupta S, Sohn ASW, Mukhopadhyay S, Lin EY, Parker SJ, Banh RS, Paulo JA, Wen KW, Debnath J, Kim GE, Mancias JD, Fearon DT, Perera RM, Kimmelman AC. Yamamoto K, et al. Among authors: kimmelman ac. Nature. 2020 May;581(7806):100-105. doi: 10.1038/s41586-020-2229-5. Epub 2020 Apr 22. Nature. 2020. PMID: 32376951 Free PMC article.
Genetics and biology of pancreatic ductal adenocarcinoma.
Hezel AF, Kimmelman AC, Stanger BZ, Bardeesy N, Depinho RA. Hezel AF, et al. Among authors: kimmelman ac. Genes Dev. 2006 May 15;20(10):1218-49. doi: 10.1101/gad.1415606. Genes Dev. 2006. PMID: 16702400 Free article. Review.
Stromal biology of pancreatic cancer.
Chu GC, Kimmelman AC, Hezel AF, DePinho RA. Chu GC, et al. Among authors: kimmelman ac. J Cell Biochem. 2007 Jul 1;101(4):887-907. doi: 10.1002/jcb.21209. J Cell Biochem. 2007. PMID: 17266048 Review.
p53 and Pten control neural and glioma stem/progenitor cell renewal and differentiation.
Zheng H, Ying H, Yan H, Kimmelman AC, Hiller DJ, Chen AJ, Perry SR, Tonon G, Chu GC, Ding Z, Stommel JM, Dunn KL, Wiedemeyer R, You MJ, Brennan C, Wang YA, Ligon KL, Wong WH, Chin L, DePinho RA. Zheng H, et al. Among authors: kimmelman ac. Nature. 2008 Oct 23;455(7216):1129-33. doi: 10.1038/nature07443. Nature. 2008. PMID: 18948956 Free PMC article.
Pancreatic cancers require autophagy for tumor growth.
Yang S, Wang X, Contino G, Liesa M, Sahin E, Ying H, Bause A, Li Y, Stommel JM, Dell'antonio G, Mautner J, Tonon G, Haigis M, Shirihai OS, Doglioni C, Bardeesy N, Kimmelman AC. Yang S, et al. Among authors: kimmelman ac. Genes Dev. 2011 Apr 1;25(7):717-29. doi: 10.1101/gad.2016111. Epub 2011 Mar 15. Genes Dev. 2011. PMID: 21406549 Free PMC article.
A critical role for autophagy in pancreatic cancer.
Yang S, Kimmelman AC. Yang S, et al. Among authors: kimmelman ac. Autophagy. 2011 Aug;7(8):912-3. doi: 10.4161/auto.7.8.15762. Epub 2011 Aug 1. Autophagy. 2011. PMID: 21494085
The dynamic nature of autophagy in cancer.
Kimmelman AC. Kimmelman AC. Genes Dev. 2011 Oct 1;25(19):1999-2010. doi: 10.1101/gad.17558811. Genes Dev. 2011. PMID: 21979913 Free PMC article. Review.
Targeting autophagy addiction in cancer.
Mancias JD, Kimmelman AC. Mancias JD, et al. Among authors: kimmelman ac. Oncotarget. 2011 Dec;2(12):1302-6. doi: 10.18632/oncotarget.384. Oncotarget. 2011. PMID: 22185891 Free PMC article.
Glutamine supports pancreatic cancer growth through a KRAS-regulated metabolic pathway.
Son J, Lyssiotis CA, Ying H, Wang X, Hua S, Ligorio M, Perera RM, Ferrone CR, Mullarky E, Shyh-Chang N, Kang Y, Fleming JB, Bardeesy N, Asara JM, Haigis MC, DePinho RA, Cantley LC, Kimmelman AC. Son J, et al. Among authors: kimmelman ac. Nature. 2013 Apr 4;496(7443):101-5. doi: 10.1038/nature12040. Epub 2013 Mar 27. Nature. 2013. PMID: 23535601 Free PMC article.
KRAS: feeding pancreatic cancer proliferation.
Bryant KL, Mancias JD, Kimmelman AC, Der CJ. Bryant KL, et al. Among authors: kimmelman ac. Trends Biochem Sci. 2014 Feb;39(2):91-100. doi: 10.1016/j.tibs.2013.12.004. Epub 2014 Jan 2. Trends Biochem Sci. 2014. PMID: 24388967 Free PMC article. Review.
117 results