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Page 1
Kinase-impaired BTK mutations are susceptible to clinical-stage BTK and IKZF1/3 degrader NX-2127.
Montoya S, Bourcier J, Noviski M, Lu H, Thompson MC, Chirino A, Jahn J, Sondhi AK, Gajewski S, Tan YSM, Yung S, Urban A, Wang E, Han C, Mi X, Kim WJ, Sievers Q, Auger P, Bousquet H, Brathaban N, Bravo B, Gessner M, Guiducci C, Iuliano JN, Kane T, Mukerji R, Reddy PJ, Powers J, Sanchez Garcia de Los Rios M, Ye J, Barrientos Risso C, Tsai D, Pardo G, Notti RQ, Pardo A, Affer M, Nawaratne V, Totiger TM, Pena-Velasquez C, Rhodes JM, Zelenetz AD, Alencar A, Roeker LE, Mehta S, Garippa R, Linley A, Soni RK, Skånland SS, Brown RJ, Mato AR, Hansen GM, Abdel-Wahab O, Taylor J. Montoya S, et al. Among authors: kim wj. Science. 2024 Feb 2;383(6682):eadi5798. doi: 10.1126/science.adi5798. Epub 2024 Feb 2. Science. 2024. PMID: 38301010
Acquired BAX mutations in AML.
Kim WJ, Abdel-Wahab O. Kim WJ, et al. Blood. 2023 Feb 9;141(6):562-564. doi: 10.1182/blood.2022018508. Blood. 2023. PMID: 36757728 Free PMC article. No abstract available.
Impaired Proteolysis of Noncanonical RAS Proteins Drives Clonal Hematopoietic Transformation.
Chen S, Vedula RS, Cuevas-Navarro A, Lu B, Hogg SJ, Wang E, Benbarche S, Knorr K, Kim WJ, Stanley RF, Cho H, Erickson C, Singer M, Cui D, Tittley S, Durham BH, Pavletich TS, Fiala E, Walsh MF, Inoue D, Monette S, Taylor J, Rosen N, McCormick F, Lindsley RC, Castel P, Abdel-Wahab O. Chen S, et al. Among authors: kim wj. Cancer Discov. 2022 Oct 5;12(10):2434-2453. doi: 10.1158/2159-8290.CD-21-1631. Cancer Discov. 2022. PMID: 35904492 Free PMC article.
Modulation of RNA splicing enhances response to BCL2 inhibition in leukemia.
Wang E, Pineda JMB, Kim WJ, Chen S, Bourcier J, Stahl M, Hogg SJ, Bewersdorf JP, Han C, Singer ME, Cui D, Erickson CE, Tittley SM, Penson AV, Knorr K, Stanley RF, Rahman J, Krishnamoorthy G, Fagin JA, Creger E, McMillan E, Mak CC, Jarvis M, Bossard C, Beaupre DM, Bradley RK, Abdel-Wahab O. Wang E, et al. Among authors: kim wj. Cancer Cell. 2023 Jan 9;41(1):164-180.e8. doi: 10.1016/j.ccell.2022.12.002. Epub 2022 Dec 22. Cancer Cell. 2023. PMID: 36563682 Free PMC article.
Jak2V617F Reversible Activation Shows Its Essential Requirement in Myeloproliferative Neoplasms.
Dunbar AJ, Bowman RL, Park YC, O'Connor K, Izzo F, Myers RM, Karzai A, Zaroogian Z, Kim WJ, Fernández-Maestre I, Waarts MR, Nazir A, Xiao W, Codilupi T, Brodsky M, Farina M, Cai L, Cai SF, Wang B, An W, Yang JL, Mowla S, Eisman SE, Hanasoge Somasundara AV, Glass JL, Mishra T, Houston R, Guzzardi E, Martinez Benitez AR, Viny AD, Koche RP, Meyer SC, Landau DA, Levine RL. Dunbar AJ, et al. Among authors: kim wj. Cancer Discov. 2024 May 1;14(5):737-751. doi: 10.1158/2159-8290.CD-22-0952. Cancer Discov. 2024. PMID: 38230747 Free PMC article.
Plasma Leptin and Alzheimer Protein Pathologies Among Older Adults.
Lee S, Byun MS, Yi D, Ahn H, Jung G, Jung JH, Chang YY, Kim K, Choi H, Choi J, Lee JY, Kang KM, Sohn CH, Lee YS, Kim YK, Lee DY; Korean Brain Aging Study for Early Diagnosis and Prediction of Alzheimer Disease (KBASE) Research Group. Lee S, et al. JAMA Netw Open. 2024 May 1;7(5):e249539. doi: 10.1001/jamanetworkopen.2024.9539. JAMA Netw Open. 2024. PMID: 38700863 Free PMC article.
Gold(I)-Thiolate Coordination Polymers as Multifunctional Materials: The Case of Au(I)-p-Fluorothiophenolate.
Vaidya S, Hawila S, Zeyu F, Khan T, Fateeva A, Toche F, Chiriac R, Bonhommé A, Ledoux G, Lebègue S, Park J, Kim WJ, Liu J, Guo X, Mesbah A, Horike S, Demessence A. Vaidya S, et al. Among authors: kim wj. ACS Appl Mater Interfaces. 2024 May 1;16(17):22512-22521. doi: 10.1021/acsami.4c01958. Epub 2024 Apr 23. ACS Appl Mater Interfaces. 2024. PMID: 38651627
IL4 receptor targeting enables nab-paclitaxel to enhance reprogramming of M2-type macrophages into M1-like phenotype via ROS-HMGB1-TLR4 axis and inhibition of tumor growth and metastasis.
Vadevoo SMP, Kang Y, Gunassekaran GR, Lee SM, Park MS, Jo DG, Kim SK, Lee H, Kim WJ, Lee B. Vadevoo SMP, et al. Among authors: kim wj. Theranostics. 2024 Apr 8;14(6):2605-2621. doi: 10.7150/thno.92672. eCollection 2024. Theranostics. 2024. PMID: 38646639 Free PMC article.
2,989 results