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Glucose-dependent control of leucine metabolism by leucyl-tRNA synthetase 1.
Yoon I, Nam M, Kim HK, Moon HS, Kim S, Jang J, Song JA, Jeong SJ, Kim SB, Cho S, Kim Y, Lee J, Yang WS, Yoo HC, Kim K, Kim MS, Yang A, Cho K, Park HS, Hwang GS, Hwang KY, Han JM, Kim JH, Kim S. Yoon I, et al. Among authors: kim sb, kim hk, kim s, kim ms, kim y, kim k, kim jh. Science. 2020 Jan 10;367(6474):205-210. doi: 10.1126/science.aau2753. Epub 2019 Nov 28. Science. 2020. PMID: 31780625
Control of leucine-dependent mTORC1 pathway through chemical intervention of leucyl-tRNA synthetase and RagD interaction.
Kim JH, Lee C, Lee M, Wang H, Kim K, Park SJ, Yoon I, Jang J, Zhao H, Kim HK, Kwon NH, Jeong SJ, Yoo HC, Kim JH, Yang JS, Lee MY, Lee CW, Yun J, Oh SJ, Kang JS, Martinis SA, Hwang KY, Guo M, Han G, Han JM, Kim S. Kim JH, et al. Among authors: kim hk, kim s, kim k. Nat Commun. 2017 Sep 29;8(1):732. doi: 10.1038/s41467-017-00785-0. Nat Commun. 2017. PMID: 28963468 Free PMC article.
AIMP1 negatively regulates adipogenesis by inhibiting PPARγ.
Kim JH, Lee JH, Park MC, Yoon I, Kim K, Lee M, Choi HS, Han JM, Kim S. Kim JH, et al. Among authors: kim s, kim k. J Cell Sci. 2014 Oct 15;127(Pt 20):4483-93. doi: 10.1242/jcs.154930. Epub 2014 Aug 21. J Cell Sci. 2014. PMID: 25146391
Discovery of Leucyladenylate Sulfamates as Novel Leucyl-tRNA Synthetase (LRS)-Targeted Mammalian Target of Rapamycin Complex 1 (mTORC1) Inhibitors.
Yoon S, Kim JH, Kim SE, Kim C, Tran PT, Ann J, Koh Y, Jang J, Kim S, Moon HS, Kim WK, Lee S, Lee J, Kim S, Lee J. Yoon S, et al. Among authors: kim se, kim wk, kim c, kim s, kim jh. J Med Chem. 2016 Nov 23;59(22):10322-10328. doi: 10.1021/acs.jmedchem.6b01190. Epub 2016 Nov 9. J Med Chem. 2016. PMID: 27933890
Leucine-induced localization of Leucyl-tRNA synthetase in lysosome membrane.
Choi H, Son JB, Kang J, Kwon J, Kim JH, Jung M, Kim SK, Kim S, Mun JY. Choi H, et al. Among authors: kim s, kim sk, kim jh. Biochem Biophys Res Commun. 2017 Nov 18;493(2):1129-1135. doi: 10.1016/j.bbrc.2017.09.008. Epub 2017 Sep 5. Biochem Biophys Res Commun. 2017. PMID: 28882589
31,110 results
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