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The N-Degron Pathway Mediates ER-phagy.
Ji CH, Kim HY, Heo AJ, Lee SH, Lee MJ, Kim SB, Srinivasrao G, Mun SR, Cha-Molstad H, Ciechanover A, Choi CY, Lee HG, Kim BY, Kwon YT. Ji CH, et al. Among authors: kim sb, kim hy, kim by. Mol Cell. 2019 Sep 5;75(5):1058-1072.e9. doi: 10.1016/j.molcel.2019.06.028. Epub 2019 Jul 30. Mol Cell. 2019. PMID: 31375263 Free article.
Amino-terminal arginylation targets endoplasmic reticulum chaperone BiP for autophagy through p62 binding.
Cha-Molstad H, Sung KS, Hwang J, Kim KA, Yu JE, Yoo YD, Jang JM, Han DH, Molstad M, Kim JG, Lee YJ, Zakrzewska A, Kim SH, Kim ST, Kim SY, Lee HG, Soung NK, Ahn JS, Ciechanover A, Kim BY, Kwon YT. Cha-Molstad H, et al. Among authors: kim st, kim sh, kim ka, kim sy, kim by, kim jg. Nat Cell Biol. 2015 Jul;17(7):917-29. doi: 10.1038/ncb3177. Epub 2015 Jun 15. Nat Cell Biol. 2015. PMID: 26075355 Free PMC article.
N-terminal arginylation generates a bimodal degron that modulates autophagic proteolysis.
Yoo YD, Mun SR, Ji CH, Sung KW, Kang KY, Heo AJ, Lee SH, An JY, Hwang J, Xie XQ, Ciechanover A, Kim BY, Kwon YT. Yoo YD, et al. Among authors: kim by. Proc Natl Acad Sci U S A. 2018 Mar 20;115(12):E2716-E2724. doi: 10.1073/pnas.1719110115. Epub 2018 Mar 5. Proc Natl Acad Sci U S A. 2018. PMID: 29507222 Free PMC article.
Regulation of reticulophagy by the N-degron pathway.
Ji CH, Kim HY, Heo AJ, Lee MJ, Park DY, Kim DH, Kim BY, Kwon YT. Ji CH, et al. Among authors: kim hy, kim dh, kim by. Autophagy. 2020 Feb;16(2):373-375. doi: 10.1080/15548627.2019.1695402. Epub 2019 Nov 27. Autophagy. 2020. PMID: 31744379 Free PMC article.
Glioma-derived cancer stem cells are hypersensitive to proteasomal inhibition.
Yoo YD, Lee DH, Cha-Molstad H, Kim H, Mun SR, Ji C, Park SH, Sung KS, Choi SA, Hwang J, Park DM, Kim SK, Park KJ, Kang SH, Oh SC, Ciechanover A, Lee YJ, Kim BY, Kwon YT. Yoo YD, et al. Among authors: kim h, kim by, kim sk. EMBO Rep. 2017 Jan;18(1):150-168. doi: 10.15252/embr.201642360. Epub 2016 Dec 19. EMBO Rep. 2017. PMID: 27993939 Free PMC article.
p62/SQSTM1/Sequestosome-1 is an N-recognin of the N-end rule pathway which modulates autophagosome biogenesis.
Cha-Molstad H, Yu JE, Feng Z, Lee SH, Kim JG, Yang P, Han B, Sung KW, Yoo YD, Hwang J, McGuire T, Shim SM, Song HD, Ganipisetti S, Wang N, Jang JM, Lee MJ, Kim SJ, Lee KH, Hong JT, Ciechanover A, Mook-Jung I, Kim KP, Xie XQ, Kwon YT, Kim BY. Cha-Molstad H, et al. Among authors: kim kp, kim sj, kim by, kim jg. Nat Commun. 2017 Jul 24;8(1):102. doi: 10.1038/s41467-017-00085-7. Nat Commun. 2017. PMID: 28740232 Free PMC article.
1,313 results