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Compilation and evaluation of a fatty acid mimetics screening library.
Ehrler JHM, Brunst S, Tjaden A, Kilu W, Heering J, Hernandez-Olmos V, Krommes A, Kramer JS, Steinhilber D, Schubert-Zsilavecz M, Müller S, Merk D, Proschak E. Ehrler JHM, et al. Among authors: kilu w. Biochem Pharmacol. 2022 Oct;204:115191. doi: 10.1016/j.bcp.2022.115191. Epub 2022 Jul 27. Biochem Pharmacol. 2022. PMID: 35907497
Nurr1 Modulation Mediates Neuroprotective Effects of Statins.
Willems S, Marschner JA, Kilu W, Faudone G, Busch R, Duensing-Kropp S, Heering J, Merk D. Willems S, et al. Among authors: kilu w. Adv Sci (Weinh). 2022 Jun;9(18):e2104640. doi: 10.1002/advs.202104640. Epub 2022 Apr 30. Adv Sci (Weinh). 2022. PMID: 35488520 Free PMC article.
The Transcriptional Repressor Orphan Nuclear Receptor TLX Is Responsive to Xanthines.
Faudone G, Kilu W, Ni X, Chaikuad A, Sreeramulu S, Heitel P, Schwalbe H, Knapp S, Schubert-Zsilavecz M, Heering J, Merk D. Faudone G, et al. Among authors: kilu w. ACS Pharmacol Transl Sci. 2021 Nov 23;4(6):1794-1807. doi: 10.1021/acsptsci.1c00195. eCollection 2021 Dec 10. ACS Pharmacol Transl Sci. 2021. PMID: 34927011 Free PMC article.
Structure-Based Design of Dual Partial Peroxisome Proliferator-Activated Receptor γ Agonists/Soluble Epoxide Hydrolase Inhibitors.
Lillich FF, Willems S, Ni X, Kilu W, Borkowsky C, Brodsky M, Kramer JS, Brunst S, Hernandez-Olmos V, Heering J, Schierle S, Kestner RI, Mayser FM, Helmstädter M, Göbel T, Weizel L, Namgaladze D, Kaiser A, Steinhilber D, Pfeilschifter W, Kahnt AS, Proschak A, Chaikuad A, Knapp S, Merk D, Proschak E. Lillich FF, et al. Among authors: kilu w. J Med Chem. 2021 Dec 9;64(23):17259-17276. doi: 10.1021/acs.jmedchem.1c01331. Epub 2021 Nov 24. J Med Chem. 2021. PMID: 34818007
Combined Cardioprotective and Adipocyte Browning Effects Promoted by the Eutomer of Dual sEH/PPARγ Modulator.
Hartmann M, Bibli SI, Tews D, Ni X, Kircher T, Kramer JS, Kilu W, Heering J, Hernandez-Olmos V, Weizel L, Scriba GKE, Krait S, Knapp S, Chaikuad A, Merk D, Fleming I, Fischer-Posovszky P, Proschak E. Hartmann M, et al. Among authors: kilu w. J Med Chem. 2021 Mar 11;64(5):2815-2828. doi: 10.1021/acs.jmedchem.0c02063. Epub 2021 Feb 23. J Med Chem. 2021. PMID: 33620196
Systematic Assessment of Fragment Identification for Multitarget Drug Design.
Brunst S, Kramer JS, Kilu W, Heering J, Pollinger J, Hiesinger K, George S, Steinhilber D, Merk D, Proschak E. Brunst S, et al. Among authors: kilu w. ChemMedChem. 2021 Apr 8;16(7):1088-1092. doi: 10.1002/cmdc.202000858. Epub 2021 Feb 4. ChemMedChem. 2021. PMID: 33283450 Free PMC article.
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