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NQO1-dependent, Tumor-selective Radiosensitization of Non-small Cell Lung Cancers.
Motea EA, Huang X, Singh N, Kilgore JA, Williams NS, Xie XJ, Gerber DE, Beg MS, Bey EA, Boothman DA. Motea EA, et al. Among authors: kilgore ja. Clin Cancer Res. 2019 Apr 15;25(8):2601-2609. doi: 10.1158/1078-0432.CCR-18-2560. Epub 2019 Jan 7. Clin Cancer Res. 2019. PMID: 30617135 Free PMC article.
Specific inhibition of mitochondrial oxidative stress suppresses inflammation and improves cardiac function in a rat pneumonia-related sepsis model.
Zang QS, Sadek H, Maass DL, Martinez B, Ma L, Kilgore JA, Williams NS, Frantz DE, Wigginton JG, Nwariaku FE, Wolf SE, Minei JP. Zang QS, et al. Among authors: kilgore ja. Am J Physiol Heart Circ Physiol. 2012 May 1;302(9):H1847-59. doi: 10.1152/ajpheart.00203.2011. Epub 2012 Mar 9. Am J Physiol Heart Circ Physiol. 2012. PMID: 22408027 Free article.
Leveraging an NQO1 Bioactivatable Drug for Tumor-Selective Use of Poly(ADP-ribose) Polymerase Inhibitors.
Huang X, Motea EA, Moore ZR, Yao J, Dong Y, Chakrabarti G, Kilgore JA, Silvers MA, Patidar PL, Cholka A, Fattah F, Cha Y, Anderson GG, Kusko R, Peyton M, Yan J, Xie XJ, Sarode V, Williams NS, Minna JD, Beg M, Gerber DE, Bey EA, Boothman DA. Huang X, et al. Among authors: kilgore ja. Cancer Cell. 2016 Dec 12;30(6):940-952. doi: 10.1016/j.ccell.2016.11.006. Cancer Cell. 2016. PMID: 27960087 Free PMC article.
MYC promotes tryptophan uptake and metabolism by the kynurenine pathway in colon cancer.
Venkateswaran N, Lafita-Navarro MC, Hao YH, Kilgore JA, Perez-Castro L, Braverman J, Borenstein-Auerbach N, Kim M, Lesner NP, Mishra P, Brabletz T, Shay JW, DeBerardinis RJ, Williams NS, Yilmaz OH, Conacci-Sorrell M. Venkateswaran N, et al. Among authors: kilgore ja. Genes Dev. 2019 Sep 1;33(17-18):1236-1251. doi: 10.1101/gad.327056.119. Epub 2019 Aug 15. Genes Dev. 2019. PMID: 31416966 Free PMC article.
Inhibition of the de novo pyrimidine biosynthesis pathway limits ribosomal RNA transcription causing nucleolar stress in glioblastoma cells.
Lafita-Navarro MC, Venkateswaran N, Kilgore JA, Kanji S, Han J, Barnes S, Williams NS, Buszczak M, Burma S, Conacci-Sorrell M. Lafita-Navarro MC, et al. Among authors: kilgore ja. PLoS Genet. 2020 Nov 17;16(11):e1009117. doi: 10.1371/journal.pgen.1009117. eCollection 2020 Nov. PLoS Genet. 2020. PMID: 33201894 Free PMC article.
33 results