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Advantages of a mouse model for human hearing impairment.
Kikkawa Y, Seki Y, Okumura K, Ohshiba Y, Miyasaka Y, Suzuki S, Ozaki M, Matsuoka K, Noguchi Y, Yonekawa H. Kikkawa Y, et al. Exp Anim. 2012;61(2):85-98. doi: 10.1538/expanim.61.85. Exp Anim. 2012. PMID: 22531723 Free article. Review.
Heterozygous mutation of Ush1g/Sans in mice causes early-onset progressive hearing loss, which is recovered by reconstituting the strain-specific mutation in Cdh23.
Miyasaka Y, Shitara H, Suzuki S, Yoshimoto S, Seki Y, Ohshiba Y, Okumura K, Taya C, Tokano H, Kitamura K, Takada T, Hibino H, Shiroishi T, Kominami R, Yonekawa H, Kikkawa Y. Miyasaka Y, et al. Among authors: kikkawa y. Hum Mol Genet. 2016 May 15;25(10):2045-2059. doi: 10.1093/hmg/ddw078. Epub 2016 Mar 2. Hum Mol Genet. 2016. PMID: 26936824
A novel splice site mutation of myosin VI in mice leads to stereociliary fusion caused by disruption of actin networks in the apical region of inner ear hair cells.
Seki Y, Miyasaka Y, Suzuki S, Wada K, Yasuda SP, Matsuoka K, Ohshiba Y, Endo K, Ishii R, Shitara H, Kitajiri SI, Nakagata N, Takebayashi H, Kikkawa Y. Seki Y, et al. Among authors: kikkawa y. PLoS One. 2017 Aug 23;12(8):e0183477. doi: 10.1371/journal.pone.0183477. eCollection 2017. PLoS One. 2017. PMID: 28832620 Free PMC article.
533 results