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The small-molecule SMARt751 reverses Mycobacterium tuberculosis resistance to ethionamide in acute and chronic mouse models of tuberculosis.
Flipo M, Frita R, Bourotte M, Martínez-Martínez MS, Boesche M, Boyle GW, Derimanov G, Drewes G, Gamallo P, Ghidelli-Disse S, Gresham S, Jiménez E, de Mercado J, Pérez-Herrán E, Porras-De Francisco E, Rullas J, Casado P, Leroux F, Piveteau C, Kiass M, Mathys V, Soetaert K, Megalizzi V, Tanina A, Wintjens R, Antoine R, Brodin P, Delorme V, Moune M, Djaout K, Slupek S, Kemmer C, Gitzinger M, Ballell L, Mendoza-Losana A, Lociuro S, Deprez B, Barros-Aguirre D, Remuiñán MJ, Willand N, Baulard AR. Flipo M, et al. Among authors: kiass m. Sci Transl Med. 2022 May 4;14(643):eaaz6280. doi: 10.1126/scitranslmed.aaz6280. Epub 2022 May 4. Sci Transl Med. 2022. PMID: 35507672
Reversion of antibiotic resistance in Mycobacterium tuberculosis by spiroisoxazoline SMARt-420.
Blondiaux N, Moune M, Desroses M, Frita R, Flipo M, Mathys V, Soetaert K, Kiass M, Delorme V, Djaout K, Trebosc V, Kemmer C, Wintjens R, Wohlkönig A, Antoine R, Huot L, Hot D, Coscolla M, Feldmann J, Gagneux S, Locht C, Brodin P, Gitzinger M, Déprez B, Willand N, Baulard AR. Blondiaux N, et al. Among authors: kiass m. Science. 2017 Mar 17;355(6330):1206-1211. doi: 10.1126/science.aag1006. Epub 2017 Mar 16. Science. 2017. PMID: 28302858
Molecular genetics of para-aminosalicylic acid resistance in clinical isolates and spontaneous mutants of Mycobacterium tuberculosis.
Mathys V, Wintjens R, Lefevre P, Bertout J, Singhal A, Kiass M, Kurepina N, Wang XM, Mathema B, Baulard A, Kreiswirth BN, Bifani P. Mathys V, et al. Among authors: kiass m. Antimicrob Agents Chemother. 2009 May;53(5):2100-9. doi: 10.1128/AAC.01197-08. Epub 2009 Feb 23. Antimicrob Agents Chemother. 2009. PMID: 19237648 Free PMC article.
Biological evaluation of bisbenzaldehydes against four Mycobacterium species.
Cappoen D, Forge D, Vercammen F, Mathys V, Kiass M, Roupie V, Anthonissen R, Verschaeve L, Vanden Eynde JJ, Huygen K. Cappoen D, et al. Among authors: kiass m. Eur J Med Chem. 2013 May;63:731-8. doi: 10.1016/j.ejmech.2013.03.023. Epub 2013 Mar 18. Eur J Med Chem. 2013. PMID: 23567963
Experimental tuberculosis in the Wistar rat: a model for protective immunity and control of infection.
Singhal A, Aliouat el M, Hervé M, Mathys V, Kiass M, Creusy C, Delaire B, Tsenova L, Fleurisse L, Bertout J, Camacho L, Foo D, Tay HC, Siew JY, Boukhouchi W, Romano M, Mathema B, Dartois V, Kaplan G, Bifani P. Singhal A, et al. Among authors: kiass m. PLoS One. 2011 Apr 12;6(4):e18632. doi: 10.1371/journal.pone.0018632. PLoS One. 2011. PMID: 21533270 Free PMC article.