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Paradoxical effects of obesity on T cell function during tumor progression and PD-1 checkpoint blockade.
Wang Z, Aguilar EG, Luna JI, Dunai C, Khuat LT, Le CT, Mirsoian A, Minnar CM, Stoffel KM, Sturgill IR, Grossenbacher SK, Withers SS, Rebhun RB, Hartigan-O'Connor DJ, Méndez-Lagares G, Tarantal AF, Isseroff RR, Griffith TS, Schalper KA, Merleev A, Saha A, Maverakis E, Kelly K, Aljumaily R, Ibrahimi S, Mukherjee S, Machiorlatti M, Vesely SK, Longo DL, Blazar BR, Canter RJ, Murphy WJ, Monjazeb AM. Wang Z, et al. Among authors: khuat lt. Nat Med. 2019 Jan;25(1):141-151. doi: 10.1038/s41591-018-0221-5. Epub 2018 Nov 12. Nat Med. 2019. PMID: 30420753 Free PMC article.
Licensing delineates helper and effector NK cell subsets during viral infection.
Zamora AE, Aguilar EG, Sungur CM, Khuat LT, Dunai C, Lochhead GR, Du J, Pomeroy C, Blazar BR, Longo DL, Venstrom JM, Baumgarth N, Murphy WJ. Zamora AE, et al. Among authors: khuat lt. JCI Insight. 2017 May 18;2(10):e87032. doi: 10.1172/jci.insight.87032. eCollection 2017 May 18. JCI Insight. 2017. PMID: 28515356 Free PMC article.
Minimal PD-1 expression in mouse and human NK cells under diverse conditions.
Judge SJ, Dunai C, Aguilar EG, Vick SC, Sturgill IR, Khuat LT, Stoffel KM, Van Dyke J, Longo DL, Darrow MA, Anderson SK, Blazar BR, Monjazeb AM, Serody JS, Canter RJ, Murphy WJ. Judge SJ, et al. Among authors: khuat lt. J Clin Invest. 2020 Jun 1;130(6):3051-3068. doi: 10.1172/JCI133353. J Clin Invest. 2020. PMID: 32134744 Free PMC article.
PD-1 Blockade Reverses Obesity-Mediated T Cell Priming Impairment.
Le CT, Khuat LT, Caryotakis SE, Wang M, Dunai C, Nguyen AV, Vick LV, Stoffel KM, Blazar BR, Monjazeb AM, Murphy WJ, Soulika AM. Le CT, et al. Among authors: khuat lt. Front Immunol. 2020 Oct 29;11:590568. doi: 10.3389/fimmu.2020.590568. eCollection 2020. Front Immunol. 2020. PMID: 33193426 Free PMC article.
Obesity induces gut microbiota alterations and augments acute graft-versus-host disease after allogeneic stem cell transplantation.
Khuat LT, Le CT, Pai CS, Shields-Cutler RR, Holtan SG, Rashidi A, Parker SL, Knights D, Luna JI, Dunai C, Wang Z, Sturgill IR, Stoffel KM, Merleev AA, More SK, Maverakis E, Raybould HE, Chen M, Canter RJ, Monjazeb AM, Dave M, Ferrara JLM, Levine JE, Longo DL, Abedi M, Blazar BR, Murphy WJ. Khuat LT, et al. Sci Transl Med. 2020 Nov 25;12(571):eaay7713. doi: 10.1126/scitranslmed.aay7713. Sci Transl Med. 2020. PMID: 33239390 Free PMC article.
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