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Modulating Antibody Structure and Function through Directed Mutations and Chemical Rescue.
ACS Synth Biol. 2018 Apr 20;7(4):1152-1162. doi: 10.1021/acssynbio.8b00124. Epub 2018 Apr 9.
ACS Synth Biol. 2018.
PMID: 29609459
Free PMC article.
Computational Design of an Allosteric Antibody Switch by Deletion and Rescue of a Complex Structural Constellation.
Khowsathit J, Bazzoli A, Cheng H, Karanicolas J.
Khowsathit J, et al.
ACS Cent Sci. 2020 Mar 25;6(3):390-403. doi: 10.1021/acscentsci.9b01065. Epub 2020 Mar 11.
ACS Cent Sci. 2020.
PMID: 32232139
Free PMC article.
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Target-Based Design of Promysalin Analogues Identifies a New Putative Binding Cleft in Succinate Dehydrogenase.
Post SJ, Keohane CE, Rossiter LM, Kaplan AR, Khowsathit J, Matuska K, Karanicolas J, Wuest WM.
Post SJ, et al. Among authors: khowsathit j.
ACS Infect Dis. 2020 Jun 12;6(6):1372-1377. doi: 10.1021/acsinfecdis.0c00024. Epub 2020 Apr 14.
ACS Infect Dis. 2020.
PMID: 32286041
Free PMC article.
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Promysalin Elicits Species-Selective Inhibition of Pseudomonas aeruginosa by Targeting Succinate Dehydrogenase.
Keohane CE, Steele AD, Fetzer C, Khowsathit J, Van Tyne D, Moynié L, Gilmore MS, Karanicolas J, Sieber SA, Wuest WM.
Keohane CE, et al. Among authors: khowsathit j.
J Am Chem Soc. 2018 Feb 7;140(5):1774-1782. doi: 10.1021/jacs.7b11212. Epub 2018 Jan 24.
J Am Chem Soc. 2018.
PMID: 29300464
Free PMC article.
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DARC: Mapping Surface Topography by Ray-Casting for Effective Virtual Screening at Protein Interaction Sites.
Gowthaman R, Miller SA, Rogers S, Khowsathit J, Lan L, Bai N, Johnson DK, Liu C, Xu L, Anbanandam A, Aubé J, Roy A, Karanicolas J.
Gowthaman R, et al. Among authors: khowsathit j.
J Med Chem. 2016 May 12;59(9):4152-70. doi: 10.1021/acs.jmedchem.5b00150. Epub 2015 Jul 10.
J Med Chem. 2016.
PMID: 26126123
Free PMC article.
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Targeting CDK9 Reactivates Epigenetically Silenced Genes in Cancer.
Zhang H, Pandey S, Travers M, Sun H, Morton G, Madzo J, Chung W, Khowsathit J, Perez-Leal O, Barrero CA, Merali C, Okamoto Y, Sato T, Pan J, Garriga J, Bhanu NV, Simithy J, Patel B, Huang J, Raynal NJ, Garcia BA, Jacobson MA, Kadoch C, Merali S, Zhang Y, Childers W, Abou-Gharbia M, Karanicolas J, Baylin SB, Zahnow CA, Jelinek J, Graña X, Issa JJ.
Zhang H, et al. Among authors: khowsathit j.
Cell. 2018 Nov 15;175(5):1244-1258.e26. doi: 10.1016/j.cell.2018.09.051. Epub 2018 Oct 25.
Cell. 2018.
PMID: 30454645
Free PMC article.
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Correction to "Target-Based Design of Promysalin Analogs Identifies a New Putative Binding Cleft in Succinate Dehydrogenase".
Post SJ, Keohane CE, Rossiter LM, Kaplan AR, Khowsathit J, Matuska K, Karanicolas J, Wuest WM.
Post SJ, et al. Among authors: khowsathit j.
ACS Infect Dis. 2022 Jul 8;8(7):1376. doi: 10.1021/acsinfecdis.2c00256. Epub 2022 Jun 6.
ACS Infect Dis. 2022.
PMID: 35801300
No abstract available.
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