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Integrative analysis of neuroblastoma by single-cell RNA sequencing identifies the NECTIN2-TIGIT axis as a target for immunotherapy.
Cancer Cell. 2024 Feb 12;42(2):283-300.e8. doi: 10.1016/j.ccell.2023.12.008. Epub 2024 Jan 4.
Cancer Cell. 2024.
PMID: 38181797
Free PMC article.
αβ-T Cells Engineered to Express γδ-T Cell Receptors Can Kill Neuroblastoma Organoids Independent of MHC-I Expression.
Strijker JGM, Pscheid R, Drent E, van der Hoek JJF, Koopmans B, Ober K, van Hooff SR, Kholosy WM, Cornel AM, Coomans C, Bisso A, van Loenen MM, Molenaar JJ, Wienke J.
Strijker JGM, et al. Among authors: kholosy wm.
J Pers Med. 2021 Sep 17;11(9):923. doi: 10.3390/jpm11090923.
J Pers Med. 2021.
PMID: 34575700
Free PMC article.
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Simple, fast and efficient iTOP-mediated delivery of CRISPR/Cas9 RNP in difficult-to-transduce human cells including primary T cells.
Kholosy WM, Visscher M, Ogink K, Buttstedt H, Griffin K, Beier A, Gerlach JP, Molenaar JJ, Geijsen N, de Boer M, Chatsisvili A.
Kholosy WM, et al.
J Biotechnol. 2021 Sep 10;338:71-80. doi: 10.1016/j.jbiotec.2021.07.006. Epub 2021 Jul 13.
J Biotechnol. 2021.
PMID: 34271056
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G-CSF as a suitable alternative to GM-CSF to boost dinutuximab-mediated neutrophil cytotoxicity in neuroblastoma treatment.
Martinez Sanz P, van Rees DJ, van Zogchel LMJ, Klein B, Bouti P, Olsman H, Schornagel K, Kok I, Sunak A, Leeuwenburg K, Timmerman I, Dierselhuis MP, Kholosy WM, Molenaar JJ, van Bruggen R, van den Berg TK, Kuijpers TW, Matlung HL, Tytgat GAM, Franke K.
Martinez Sanz P, et al. Among authors: kholosy wm.
J Immunother Cancer. 2021 May;9(5):e002259. doi: 10.1136/jitc-2020-002259.
J Immunother Cancer. 2021.
PMID: 34049929
Free PMC article.
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Tumor to normal single-cell mRNA comparisons reveal a pan-neuroblastoma cancer cell.
Kildisiute G, Kholosy WM, Young MD, Roberts K, Elmentaite R, van Hooff SR, Pacyna CN, Khabirova E, Piapi A, Thevanesan C, Bugallo-Blanco E, Burke C, Mamanova L, Keller KM, Langenberg-Ververgaert KPS, Lijnzaad P, Margaritis T, Holstege FCP, Tas ML, Wijnen MHWA, van Noesel MM, Del Valle I, Barone G, van der Linden R, Duncan C, Anderson J, Achermann JC, Haniffa M, Teichmann SA, Rampling D, Sebire NJ, He X, de Krijger RR, Barker RA, Meyer KB, Bayraktar O, Straathof K, Molenaar JJ, Behjati S.
Kildisiute G, et al. Among authors: kholosy wm.
Sci Adv. 2021 Feb 5;7(6):eabd3311. doi: 10.1126/sciadv.abd3311. Print 2021 Feb.
Sci Adv. 2021.
PMID: 33547074
Free PMC article.
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Anti-GD2-IRDye800CW as a targeted probe for fluorescence-guided surgery in neuroblastoma.
Wellens LM, Deken MM, Sier CFM, Johnson HR, de la Jara Ortiz F, Bhairosingh SS, Houvast RD, Kholosy WM, Baart VM, Pieters AMMJ, de Krijger RR, Molenaar JJ, Wehrens EJ, Dekkers JF, Wijnen MHWA, Vahrmeijer AL, Rios AC.
Wellens LM, et al. Among authors: kholosy wm.
Sci Rep. 2020 Oct 19;10(1):17667. doi: 10.1038/s41598-020-74464-4.
Sci Rep. 2020.
PMID: 33077751
Free PMC article.
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TBX2 is a neuroblastoma core regulatory circuitry component enhancing MYCN/FOXM1 reactivation of DREAM targets.
Decaesteker B, Denecker G, Van Neste C, Dolman EM, Van Loocke W, Gartlgruber M, Nunes C, De Vloed F, Depuydt P, Verboom K, Rombaut D, Loontiens S, De Wyn J, Kholosy WM, Koopmans B, Essing AHW, Herrmann C, Dreidax D, Durinck K, Deforce D, Van Nieuwerburgh F, Henssen A, Versteeg R, Boeva V, Schleiermacher G, van Nes J, Mestdagh P, Vanhauwaert S, Schulte JH, Westermann F, Molenaar JJ, De Preter K, Speleman F.
Decaesteker B, et al. Among authors: kholosy wm.
Nat Commun. 2018 Nov 19;9(1):4866. doi: 10.1038/s41467-018-06699-9.
Nat Commun. 2018.
PMID: 30451831
Free PMC article.
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