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Promoter engineering-mediated Tuning of esterase and transaminase expression for the chemoenzymatic synthesis of sitagliptin phosphate at the kilogram-scale.
Biotechnol Bioeng. 2021 Aug;118(8):3263-3268. doi: 10.1002/bit.27819. Epub 2021 May 21.
Biotechnol Bioeng. 2021.
PMID: 33990942
Production of mycophenolic acid by Penicillium brevicompactum-A comparison of two methods of optimization.
Patel G, Patil MD, Soni S, Khobragade TP, Chisti Y, Banerjee UC.
Patel G, et al. Among authors: khobragade tp.
Biotechnol Rep (Amst). 2016 Aug 4;11:77-85. doi: 10.1016/j.btre.2016.07.003. eCollection 2016 Sep.
Biotechnol Rep (Amst). 2016.
PMID: 28352543
Free PMC article.
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Enzymatic synthesis of sitagliptin intermediate using a novel ω-transaminase.
Kim GH, Jeon H, Khobragade TP, Patil MD, Sung S, Yoon S, Won Y, Choi IS, Yun H.
Kim GH, et al. Among authors: khobragade tp.
Enzyme Microb Technol. 2019 Jan;120:52-60. doi: 10.1016/j.enzmictec.2018.10.003. Epub 2018 Oct 6.
Enzyme Microb Technol. 2019.
PMID: 30396399
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An Integrated Cofactor/Co-Product Recycling Cascade for the Biosynthesis of Nylon Monomers from Cycloalkylamines.
Sarak S, Sung S, Jeon H, Patil MD, Khobragade TP, Pagar AD, Dawson PE, Yun H.
Sarak S, et al. Among authors: khobragade tp.
Angew Chem Int Ed Engl. 2021 Feb 15;60(7):3481-3486. doi: 10.1002/anie.202012658. Epub 2020 Dec 15.
Angew Chem Int Ed Engl. 2021.
PMID: 33140477
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Synthesis of Sitagliptin Intermediate by a Multi-Enzymatic Cascade System Using Lipase and Transaminase With Benzylamine as an Amino Donor.
Khobragade TP, Sarak S, Pagar AD, Jeon H, Giri P, Yun H.
Khobragade TP, et al.
Front Bioeng Biotechnol. 2021 Oct 6;9:757062. doi: 10.3389/fbioe.2021.757062. eCollection 2021.
Front Bioeng Biotechnol. 2021.
PMID: 34692666
Free PMC article.
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Non-Canonical Amino Acid-Based Engineering of (R)-Amine Transaminase.
Pagar AD, Jeon H, Khobragade TP, Sarak S, Giri P, Lim S, Yoo TH, Ko BJ, Yun H.
Pagar AD, et al. Among authors: khobragade tp.
Front Chem. 2022 Feb 28;10:839636. doi: 10.3389/fchem.2022.839636. eCollection 2022.
Front Chem. 2022.
PMID: 35295971
Free PMC article.
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Dual-function transaminases with hybrid nanoflower for the production of value-added chemicals from biobased levulinic acid.
Khobragade TP, Giri P, Pagar AD, Patil MD, Sarak S, Joo S, Goh Y, Jung S, Yoon H, Yun S, Kwon Y, Yun H.
Khobragade TP, et al.
Front Bioeng Biotechnol. 2023 Nov 16;11:1280464. doi: 10.3389/fbioe.2023.1280464. eCollection 2023.
Front Bioeng Biotechnol. 2023.
PMID: 38033815
Free PMC article.
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