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d-2-Hydroxyglutarate is an anti-inflammatory immunometabolite that accumulates in macrophages after TLR4 activation.
de Goede KE, Harber KJ, Gorki FS, Verberk SGS, Groh LA, Keuning ED, Struys EA, van Weeghel M, Haschemi A, de Winther MPJ, van Dierendonck XAMH, Van den Bossche J. de Goede KE, et al. Among authors: keuning ed. Biochim Biophys Acta Mol Basis Dis. 2022 Sep 1;1868(9):166427. doi: 10.1016/j.bbadis.2022.166427. Epub 2022 May 6. Biochim Biophys Acta Mol Basis Dis. 2022. PMID: 35526742 Free article.
Palmitoylated antigens for the induction of anti-tumor CD8+ T cells and enhanced tumor recognition.
Stolk DA, Horrevorts SK, Schetters STT, Kruijssen LJW, Duinkerken S, Keuning E, Ambrosini M, Kalay H, van de Ven R, Garcia-Vallejo JJ, de Gruijl TD, van Vliet SJ, van Kooyk Y. Stolk DA, et al. Among authors: keuning e. Mol Ther Oncolytics. 2021 Apr 29;21:315-328. doi: 10.1016/j.omto.2021.04.009. eCollection 2021 Jun 25. Mol Ther Oncolytics. 2021. PMID: 34141869 Free PMC article.
Myeloid ATP Citrate Lyase Regulates Macrophage Inflammatory Responses In Vitro Without Altering Inflammatory Disease Outcomes.
Verberk SGS, van der Zande HJP, Baardman J, de Goede KE, Harber KJ, Keuning ED, Lambooij JM, Otto F, Zawistowska-Deniziak A, de Vries HE, de Winther MPJ, Guigas B, Van den Bossche J. Verberk SGS, et al. Among authors: keuning ed. Front Immunol. 2021 Apr 26;12:669920. doi: 10.3389/fimmu.2021.669920. eCollection 2021. Front Immunol. 2021. PMID: 33981315 Free PMC article.
33 results