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Therapeutic potential of the Proprotein Convertase Subtilisin/Kexin family in vascular disease.
Suur BE, Chemaly M, Lindquist Liljeqvist M, Djordjevic D, Stenemo M, Bergman O, Karlöf E, Lengquist M, Odeberg J, Hurt-Camejo E, Eriksson P, Ketelhuth DFJ, Roy J, Hedin U, Nyberg M, Matic L. Suur BE, et al. Among authors: ketelhuth dfj. Front Pharmacol. 2022 Sep 15;13:988561. doi: 10.3389/fphar.2022.988561. eCollection 2022. Front Pharmacol. 2022. PMID: 36188622 Free PMC article.
3-Hydroxyanthralinic acid metabolism controls the hepatic SREBP/lipoprotein axis, inhibits inflammasome activation in macrophages, and decreases atherosclerosis in Ldlr-/- mice.
Berg M, Polyzos KA, Agardh H, Baumgartner R, Forteza MJ, Kareinen I, Gisterå A, Bottcher G, Hurt-Camejo E, Hansson GK, Ketelhuth DFJ. Berg M, et al. Among authors: ketelhuth dfj. Cardiovasc Res. 2020 Oct 1;116(12):1948-1957. doi: 10.1093/cvr/cvz258. Cardiovasc Res. 2020. PMID: 31589306 Free PMC article.
Ikk2-mediated inflammatory activation of arterial endothelial cells promotes the development and progression of atherosclerosis.
Mussbacher M, Salzmann M, Haigl B, Basílio J, Hochreiter B, Gleitsmann V, Moser B, Hoesel B, Suur BE, Puhm F, Ungerböck C, Kuttke M, Forteza MJ, Binder CJ, Ketelhuth DFJ, Assinger A, Schmid JA. Mussbacher M, et al. Among authors: ketelhuth dfj. Atherosclerosis. 2020 Aug;307:21-31. doi: 10.1016/j.atherosclerosis.2020.06.005. Epub 2020 Jul 6. Atherosclerosis. 2020. PMID: 32711212
Pyruvate dehydrogenase kinase regulates vascular inflammation in atherosclerosis and increases cardiovascular risk.
Forteza MJ, Berg M, Edsfeldt A, Sun J, Baumgartner R, Kareinen I, Casagrande FB, Hedin U, Zhang S, Vuckovic I, Dzeja PP, Polyzos KA, Gisterå A, Trauelsen M, Schwartz TW, Dib L, Herrmann J, Monaco C, Matic L, Gonçalves I, Ketelhuth DFJ. Forteza MJ, et al. Among authors: ketelhuth dfj. Cardiovasc Res. 2023 Jul 4;119(7):1524-1536. doi: 10.1093/cvr/cvad038. Cardiovasc Res. 2023. PMID: 36866436 Free PMC article.
Neil3-dependent base excision repair regulates lipid metabolism and prevents atherosclerosis in Apoe-deficient mice.
Skarpengland T, Holm S, Scheffler K, Gregersen I, Dahl TB, Suganthan R, Segers FM, Østlie I, Otten JJ, Luna L, Ketelhuth DF, Lundberg AM, Neurauter CG, Hildrestrand G, Skjelland M, Bjørndal B, Svardal AM, Iversen PO, Hedin U, Nygård S, Olstad OK, Krohg-Sørensen K, Slupphaug G, Eide L, Kuśnierczyk A, Folkersen L, Ueland T, Berge RK, Hansson GK, Biessen EA, Halvorsen B, Bjørås M, Aukrust P. Skarpengland T, et al. Sci Rep. 2016 Jun 22;6:28337. doi: 10.1038/srep28337. Sci Rep. 2016. PMID: 27328939 Free PMC article.
Germinal Center-Derived Antibodies Promote Atherosclerosis Plaque Size and Stability.
Centa M, Jin H, Hofste L, Hellberg S, Busch A, Baumgartner R, Verzaal NJ, Lind Enoksson S, Perisic Matic L, Boddul SV, Atzler D, Li DY, Sun C, Hansson GK, Ketelhuth DFJ, Hedin U, Wermeling F, Lutgens E, Binder CJ, Maegdesfessel L, Malin SG. Centa M, et al. Among authors: ketelhuth dfj. Circulation. 2019 May 21;139(21):2466-2482. doi: 10.1161/CIRCULATIONAHA.118.038534. Circulation. 2019. PMID: 30894016
80 results