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Functionally diverse type V CRISPR-Cas systems.
Science. 2019 Jan 4;363(6422):88-91. doi: 10.1126/science.aav7271. Epub 2018 Dec 6.
Science. 2019.
PMID: 30523077
Engineered Cas12i2 is a versatile high-efficiency platform for therapeutic genome editing.
McGaw C, Garrity AJ, Munoz GZ, Haswell JR, Sengupta S, Keston-Smith E, Hunnewell P, Ornstein A, Bose M, Wessells Q, Jakimo N, Yan P, Zhang H, Alfonse LE, Ziblat R, Carte JM, Lu WC, Cerchione D, Hilbert B, Sothiselvam S, Yan WX, Cheng DR, Scott DA, DiTommaso T, Chong S.
McGaw C, et al. Among authors: keston smith e.
Nat Commun. 2022 May 20;13(1):2833. doi: 10.1038/s41467-022-30465-7.
Nat Commun. 2022.
PMID: 35595757
Free PMC article.
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SMOOT libraries and phage-induced directed evolution of Cas9 to engineer reduced off-target activity.
Cerchione D, Loveluck K, Tillotson EL, Harbinski F, DaSilva J, Kelley CP, Keston-Smith E, Fernandez CA, Myer VE, Jayaram H, Steinberg BE.
Cerchione D, et al. Among authors: keston smith e.
PLoS One. 2020 Apr 16;15(4):e0231716. doi: 10.1371/journal.pone.0231716. eCollection 2020.
PLoS One. 2020.
PMID: 32298334
Free PMC article.
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Prediction of Active Site and Distal Residues in E. coli DNA Polymerase III alpha Polymerase Activity.
Parasuram R, Coulther TA, Hollander JM, Keston-Smith E, Ondrechen MJ, Beuning PJ.
Parasuram R, et al. Among authors: keston smith e.
Biochemistry. 2018 Feb 20;57(7):1063-1072. doi: 10.1021/acs.biochem.7b01004. Epub 2018 Jan 31.
Biochemistry. 2018.
PMID: 29341605
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