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Design, synthesis and biological evaluations of a long-acting, hypoxia-activated prodrug of fasudil, a ROCK inhibitor, to reduce its systemic side-effects.
Al-Hilal TA, Hossain MA, Alobaida A, Alam F, Keshavarz A, Nozik-Grayck E, Stenmark KR, German NA, Ahsan F. Al-Hilal TA, et al. Among authors: keshavarz a. J Control Release. 2021 Jun 10;334:237-247. doi: 10.1016/j.jconrel.2021.04.030. Epub 2021 Apr 26. J Control Release. 2021. PMID: 33915222 Free PMC article.
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