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Automated antigen assays display a high heterogeneity for the detection of SARS-CoV-2 variants of concern, including several Omicron sublineages.
Osterman A, Krenn F, Iglhaut M, Badell I, Lehner A, Späth PM, Stern M, Both H, Bender S, Muenchhoff M, Graf A, Krebs S, Blum H, Grimmer T, Durner J, Czibere L, Dächert C, Grzimek-Koschewa N, Protzer U, Kaderali L, Baldauf HM, Keppler OT. Osterman A, et al. Among authors: keppler ot. Med Microbiol Immunol. 2023 Oct;212(5):307-322. doi: 10.1007/s00430-023-00774-9. Epub 2023 Aug 10. Med Microbiol Immunol. 2023. PMID: 37561226 Free PMC article.
Immunologic Effect of Bivalent mRNA Booster in Patients Undergoing Hemodialysis.
Huth L, Schäfer L, Almanzar G, Lupoli G, Bischof M, Wratil PR, Stövesand T, Drechsler C, Keppler OT, Prelog M. Huth L, et al. Among authors: keppler ot. N Engl J Med. 2023 Mar 9;388(10):950-952. doi: 10.1056/NEJMc2216309. Epub 2023 Feb 15. N Engl J Med. 2023. PMID: 36791308 Free PMC article. No abstract available.
Potent high-avidity neutralizing antibodies and T cell responses after COVID-19 vaccination in individuals with B cell lymphoma and multiple myeloma.
Keppler-Hafkemeyer A, Greil C, Wratil PR, Shoumariyeh K, Stern M, Hafkemeyer A, Ashok D, Hollaus A, Lupoli G, Priller A, Bischof ML, Ihorst G, Engelhardt M, Marks R, Finke J, Bertrand H, Dächert C, Muenchhoff M, Badell I, Emmerich F, Halder H, Spaeth PM, Knolle PA, Protzer U, von Bergwelt-Baildon M, Duyster J, Hartmann TN, Moosmann A, Keppler OT. Keppler-Hafkemeyer A, et al. Among authors: keppler ot. Nat Cancer. 2023 Jan;4(1):81-95. doi: 10.1038/s43018-022-00502-x. Epub 2022 Dec 21. Nat Cancer. 2023. PMID: 36543907 Free PMC article.
HIV-1 antagonism of CD317 is species specific and involves Vpu-mediated proteasomal degradation of the restriction factor.
Goffinet C, Allespach I, Homann S, Tervo HM, Habermann A, Rupp D, Oberbremer L, Kern C, Tibroni N, Welsch S, Krijnse-Locker J, Banting G, Kräusslich HG, Fackler OT, Keppler OT. Goffinet C, et al. Among authors: keppler ot. Cell Host Microbe. 2009 Mar 19;5(3):285-97. doi: 10.1016/j.chom.2009.01.009. Cell Host Microbe. 2009. PMID: 19286137 Free article.
SAMHD1 restricts HIV-1 infection in resting CD4(+) T cells.
Baldauf HM, Pan X, Erikson E, Schmidt S, Daddacha W, Burggraf M, Schenkova K, Ambiel I, Wabnitz G, Gramberg T, Panitz S, Flory E, Landau NR, Sertel S, Rutsch F, Lasitschka F, Kim B, König R, Fackler OT, Keppler OT. Baldauf HM, et al. Among authors: keppler ot. Nat Med. 2012 Nov;18(11):1682-7. doi: 10.1038/nm.2964. Nat Med. 2012. PMID: 22972397 Free PMC article.
SAMHD1's protein expression profile in humans.
Schmidt S, Schenkova K, Adam T, Erikson E, Lehmann-Koch J, Sertel S, Verhasselt B, Fackler OT, Lasitschka F, Keppler OT. Schmidt S, et al. Among authors: keppler ot. J Leukoc Biol. 2015 Jul;98(1):5-14. doi: 10.1189/jlb.4HI0714-338RR. Epub 2015 Feb 2. J Leukoc Biol. 2015. PMID: 25646359 Free PMC article.
Vpx overcomes a SAMHD1-independent block to HIV reverse transcription that is specific to resting CD4 T cells.
Baldauf HM, Stegmann L, Schwarz SM, Ambiel I, Trotard M, Martin M, Burggraf M, Lenzi GM, Lejk H, Pan X, Fregoso OI, Lim ES, Abraham L, Nguyen LA, Rutsch F, König R, Kim B, Emerman M, Fackler OT, Keppler OT. Baldauf HM, et al. Among authors: keppler ot. Proc Natl Acad Sci U S A. 2017 Mar 7;114(10):2729-2734. doi: 10.1073/pnas.1613635114. Epub 2017 Feb 22. Proc Natl Acad Sci U S A. 2017. PMID: 28228523 Free PMC article.
173 results