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Safety pharmacology--current and emerging concepts.
Hamdam J, Sethu S, Smith T, Alfirevic A, Alhaidari M, Atkinson J, Ayala M, Box H, Cross M, Delaunois A, Dermody A, Govindappa K, Guillon JM, Jenkins R, Kenna G, Lemmer B, Meecham K, Olayanju A, Pestel S, Rothfuss A, Sidaway J, Sison-Young R, Smith E, Stebbings R, Tingle Y, Valentin JP, Williams A, Williams D, Park K, Goldring C. Hamdam J, et al. Among authors: kenna g. Toxicol Appl Pharmacol. 2013 Dec 1;273(2):229-41. doi: 10.1016/j.taap.2013.04.039. Epub 2013 Jun 1. Toxicol Appl Pharmacol. 2013. PMID: 23732082 Review.
Read-across and new approach methodologies applied in a 10-step framework for cosmetics safety assessment - A case study with parabens.
Ouedraogo G, Alexander-White C, Bury D, Clewell HJ 3rd, Cronin M, Cull T, Dent M, Desprez B, Detroyer A, Ellison C, Giammanco S, Hack E, Hewitt NJ, Kenna G, Klaric M, Kreiling R, Lester C, Mahony C, Mombelli E, Naciff J, O'Brien J, Schepky A, Tozer S, van der Burg B, van Vugt-Lussenburg B, Stuard S, Cosmetics Europe. Ouedraogo G, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Jul;132:105161. doi: 10.1016/j.yrtph.2022.105161. Epub 2022 May 1. Regul Toxicol Pharmacol. 2022. PMID: 35508214 Free article.
A 10-step framework for use of read-across (RAX) in next generation risk assessment (NGRA) for cosmetics safety assessment.
Alexander-White C, Bury D, Cronin M, Dent M, Hack E, Hewitt NJ, Kenna G, Naciff J, Ouedraogo G, Schepky A, Mahony C, Europe C. Alexander-White C, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Mar;129:105094. doi: 10.1016/j.yrtph.2021.105094. Epub 2022 Jan 4. Regul Toxicol Pharmacol. 2022. PMID: 34990780 Free article.
New framework for a non-animal approach adequately assures the safety of cosmetic ingredients - A case study on caffeine.
Bury D, Alexander-White C, Clewell HJ 3rd, Cronin M, Desprez B, Detroyer A, Efremenko A, Firman J, Hack E, Hewitt NJ, Kenna G, Klaric M, Lester C, Mahony C, Ouedraogo G, Paini A, Schepky A; Cosmetics Europe. Bury D, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2021 Jul;123:104931. doi: 10.1016/j.yrtph.2021.104931. Epub 2021 Apr 24. Regul Toxicol Pharmacol. 2021. PMID: 33905778 Free article.
Use of in vitro metabolism and biokinetics assays to refine predicted in vivo and in vitro internal exposure to the cosmetic ingredient, phenoxyethanol, for use in risk assessment.
Hewitt NJ, Troutman J, Przibilla J, Schepky A, Ouédraogo G, Mahony C, Kenna G, Varçin M, Dent MP; Cosmetics Europe. Electronic address: cosmeticseurope@cosmeticseurope.eu. Hewitt NJ, et al. Among authors: kenna g. Regul Toxicol Pharmacol. 2022 Jun;131:105132. doi: 10.1016/j.yrtph.2022.105132. Epub 2022 Feb 22. Regul Toxicol Pharmacol. 2022. PMID: 35217105 Free article.
75 results