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Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel JP, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: kenison je. Nature. 2024 Mar;627(8005):865-872. doi: 10.1038/s41586-024-07187-5. Epub 2024 Mar 20. Nature. 2024. PMID: 38509377
Disease-associated astrocyte epigenetic memory promotes CNS pathology.
Lee HG, Rone JM, Li Z, Akl CF, Shin SW, Lee JH, Flausino LE, Pernin F, Chao CC, Kleemann KL, Srun L, Illouz T, Giovannoni F, Charabati M, Sanmarco LM, Kenison JE, Piester G, Zandee SEJ, Antel J, Rothhammer V, Wheeler MA, Prat A, Clark IC, Quintana FJ. Lee HG, et al. Among authors: kenison je. bioRxiv [Preprint]. 2024 Jan 5:2024.01.04.574196. doi: 10.1101/2024.01.04.574196. bioRxiv. 2024. PMID: 38260616 Free PMC article. Updated. Preprint.
Lactate limits CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Fernandez Lahore G, Giovannoni F, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Faust Akl C, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Stevens NA, Piester G, Chung EN, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Among authors: kenison je. Nature. 2023 Aug;620(7975):881-889. doi: 10.1038/s41586-023-06409-6. Epub 2023 Aug 9. Nature. 2023. PMID: 37558878 Free PMC article.
Engineered probiotics limit CNS autoimmunity by stabilizing HIF-1α in dendritic cells.
Sanmarco LM, Rone JM, Polonio CM, Giovannoni F, Lahore GF, Ferrara K, Gutierrez-Vazquez C, Li N, Sokolovska A, Plasencia A, Akl CF, Nanda P, Heck ES, Li Z, Lee HG, Chao CC, Rejano-Gordillo CM, Fonseca-Castro PH, Illouz T, Linnerbauer M, Kenison JE, Barilla RM, Farrenkopf D, Piester G, Dailey L, Kuchroo VK, Hava D, Wheeler MA, Clish C, Nowarski R, Balsa E, Lora JM, Quintana FJ. Sanmarco LM, et al. Among authors: kenison je. bioRxiv [Preprint]. 2023 Mar 21:2023.03.17.532101. doi: 10.1101/2023.03.17.532101. bioRxiv. 2023. PMID: 36993446 Free PMC article. Updated. Preprint.
Identification of environmental factors that promote intestinal inflammation.
Sanmarco LM, Chao CC, Wang YC, Kenison JE, Li Z, Rone JM, Rejano-Gordillo CM, Polonio CM, Gutierrez-Vazquez C, Piester G, Plasencia A, Li L, Giovannoni F, Lee HG, Faust Akl C, Wheeler MA, Mascanfroni I, Jaronen M, Alsuwailm M, Hewson P, Yeste A, Andersen BM, Franks DG, Huang CJ, Ekwudo M, Tjon EC, Rothhammer V, Takenaka M, de Lima KA, Linnerbauer M, Guo L, Covacu R, Queva H, Fonseca-Castro PH, Bladi MA, Cox LM, Hodgetts KJ, Hahn ME, Mildner A, Korzenik J, Hauser R, Snapper SB, Quintana FJ. Sanmarco LM, et al. Among authors: kenison je. Nature. 2022 Nov;611(7937):801-809. doi: 10.1038/s41586-022-05308-6. Epub 2022 Oct 20. Nature. 2022. PMID: 36266581 Free PMC article.
A cell-based drug delivery platform for treating central nervous system inflammation.
Levy O, Rothhammer V, Mascanfroni I, Tong Z, Kuai R, De Biasio M, Wang Q, Majid T, Perrault C, Yeste A, Kenison JE, Safaee H, Musabeyezu J, Heinelt M, Milton Y, Kuang H, Lan H, Siders W, Multon MC, Rothblatt J, Massadeh S, Alaamery M, Alhasan AH, Quintana FJ, Karp JM. Levy O, et al. Among authors: kenison je. J Mol Med (Berl). 2021 May;99(5):663-671. doi: 10.1007/s00109-020-02003-9. Epub 2021 Jan 4. J Mol Med (Berl). 2021. PMID: 33398468 Free PMC article.
21 results