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Copper phenanthrene oxidative chemical nucleases.
Molphy Z, Prisecaru A, Slator C, Barron N, McCann M, Colleran J, Chandran D, Gathergood N, Kellett A. Molphy Z, et al. Among authors: kellett a. Inorg Chem. 2014 May 19;53(10):5392-404. doi: 10.1021/ic500914j. Epub 2014 May 7. Inorg Chem. 2014. PMID: 24806421
Synthesis, X-ray crystal structures and biomimetic and anticancer activities of novel copper(II)benzoate complexes incorporating 2-(4'-thiazolyl)benzimidazole (thiabendazole), 2-(2-pyridyl)benzimidazole and 1,10-phenanthroline as chelating nitrogen donor ligands.
Devereux M, O Shea D, Kellett A, McCann M, Walsh M, Egan D, Deegan C, Kedziora K, Rosair G, Müller-Bunz H. Devereux M, et al. Among authors: kellett a. J Inorg Biochem. 2007 Jun;101(6):881-92. doi: 10.1016/j.jinorgbio.2007.02.002. Epub 2007 Feb 14. J Inorg Biochem. 2007. PMID: 17397929
Synthesis, Superoxide Dismutase Mimetic and Anticancer Activities of Metal Complexes of 2,2-Dimethylpentanedioic Acid(2dmepdaH(2)) and 3,3-Dimethylpentanedioic acid(3dmepdaH(2)): X-Ray Crystal Structures of [Cu(3dmepda)(bipy)](2). 6H(2)O and [Cu(2dmepda)(bipy)(EtOH)](2). 4EtOH (bipy = 2,2'Bipyridine).
Devereux M, McCann M, O'shea D, O'connor M, Kiely E, McKee V, Naughton D, Fisher A, Kellett A, Walsh M, Egan D, Deegan C. Devereux M, et al. Among authors: kellett a. Bioinorg Chem Appl. 2006;2006:80283. doi: 10.1155/BCA/2006/80283. Epub 2006 Mar 20. Bioinorg Chem Appl. 2006. PMID: 17497019 Free PMC article.
Copper(II) complexes of salicylic acid combining superoxide dismutase mimetic properties with DNA binding and cleaving capabilities display promising chemotherapeutic potential with fast acting in vitro cytotoxicity against cisplatin sensitive and resistant cancer cell lines.
O'Connor M, Kellett A, McCann M, Rosair G, McNamara M, Howe O, Creaven BS, McClean S, Kia AF, O'Shea D, Devereux M. O'Connor M, et al. Among authors: kellett a. J Med Chem. 2012 Mar 8;55(5):1957-68. doi: 10.1021/jm201041d. Epub 2012 Feb 28. J Med Chem. 2012. PMID: 22313179
97 results