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Diminazene Aceturate Reduces Angiotensin II Constriction and Interacts with the Spike Protein of Severe Acute Respiratory Syndrome Coronavirus 2.
Matsoukas JM, Gadanec LK, Zulli A, Apostolopoulos V, Kelaidonis K, Ligielli I, Moschovou K, Georgiou N, Plotas P, Chasapis CT, Moore G, Ridgway H, Mavromoustakos T. Matsoukas JM, et al. Among authors: kelaidonis k. Biomedicines. 2022 Jul 18;10(7):1731. doi: 10.3390/biomedicines10071731. Biomedicines. 2022. PMID: 35885036 Free PMC article.
An efficient synthesis of a rationally designed 1,5 disubstituted imidazole AT(1) angiotensin II receptor antagonist: reorientation of imidazole pharmacophore groups in losartan reserves high receptor affinity and confirms docking studies.
Agelis G, Roumelioti P, Resvani A, Durdagi S, Androutsou ME, Kelaidonis K, Vlahakos D, Mavromoustakos T, Matsoukas J. Agelis G, et al. Among authors: kelaidonis k. J Comput Aided Mol Des. 2010 Sep;24(9):749-58. doi: 10.1007/s10822-010-9371-3. Epub 2010 Jul 10. J Comput Aided Mol Des. 2010. PMID: 20623162
Facile and efficient syntheses of a series of N-benzyl and N-biphenylmethyl substituted imidazole derivatives based on (E)-urocanic acid, as angiotensin II AT1 receptor blockers.
Agelis G, Kelaidonis K, Resvani A, Kalavrizioti D, Androutsou ME, Plotas P, Vlahakos D, Koukoulitsa C, Tselios T, Mavromoustakos T, Matsoukas J. Agelis G, et al. Among authors: kelaidonis k. Molecules. 2013 Jun 27;18(7):7510-32. doi: 10.3390/molecules18077510. Molecules. 2013. PMID: 23807577 Free PMC article.
A Global Review on Short Peptides: Frontiers and Perspectives.
Apostolopoulos V, Bojarska J, Chai TT, Elnagdy S, Kaczmarek K, Matsoukas J, New R, Parang K, Lopez OP, Parhiz H, Perera CO, Pickholz M, Remko M, Saviano M, Skwarczynski M, Tang Y, Wolf WM, Yoshiya T, Zabrocki J, Zielenkiewicz P, AlKhazindar M, Barriga V, Kelaidonis K, Sarasia EM, Toth I. Apostolopoulos V, et al. Among authors: kelaidonis k. Molecules. 2021 Jan 15;26(2):430. doi: 10.3390/molecules26020430. Molecules. 2021. PMID: 33467522 Free PMC article. Review.
Discovery of a new generation of angiotensin receptor blocking drugs: Receptor mechanisms and in silico binding to enzymes relevant to SARS-CoV-2.
Ridgway H, Moore GJ, Mavromoustakos T, Tsiodras S, Ligielli I, Kelaidonis K, Chasapis CT, Gadanec LK, Zulli A, Apostolopoulos V, Petty R, Karakasiliotis I, Gorgoulis VG, Matsoukas JM. Ridgway H, et al. Among authors: kelaidonis k. Comput Struct Biotechnol J. 2022;20:2091-2111. doi: 10.1016/j.csbj.2022.04.010. Epub 2022 Apr 9. Comput Struct Biotechnol J. 2022. PMID: 35432786 Free PMC article.
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