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Inosine induces stemness features in CAR-T cells and enhances potency.
Klysz DD, Fowler C, Malipatlolla M, Stuani L, Freitas KA, Chen Y, Meier S, Daniel B, Sandor K, Xu P, Huang J, Labanieh L, Keerthi V, Leruste A, Bashti M, Mata-Alcazar J, Gkitsas N, Guerrero JA, Fisher C, Patel S, Asano K, Patel S, Davis KL, Satpathy AT, Feldman SA, Sotillo E, Mackall CL. Klysz DD, et al. Among authors: keerthi v. Cancer Cell. 2024 Feb 12;42(2):266-282.e8. doi: 10.1016/j.ccell.2024.01.002. Epub 2024 Jan 25. Cancer Cell. 2024. PMID: 38278150 Free article.
Homology-independent targeted insertion (HITI) enables guided CAR knock-in and efficient clinical scale CAR-T cell manufacturing.
Balke-Want H, Keerthi V, Gkitsas N, Mancini AG, Kurgan GL, Fowler C, Xu P, Liu X, Asano K, Patel S, Fisher CJ, Brown AK, Tunuguntla RH, Patel S, Sotillo E, Mackall CL, Feldman SA. Balke-Want H, et al. Among authors: keerthi v. Mol Cancer. 2023 Jun 26;22(1):100. doi: 10.1186/s12943-023-01799-7. Mol Cancer. 2023. PMID: 37365642 Free PMC article.
Inosine Induces Stemness Features in CAR T cells and Enhances Potency.
Klysz DD, Fowler C, Malipatlolla M, Stuani L, Freitas KA, Meier S, Daniel B, Sandor K, Xu P, Huang J, Labanieh L, Leruste A, Bashti M, Keerthi V, Mata-Alcazar J, Gkitsas N, Guerrero JA, Fisher C, Patel S, Asano K, Patel S, Davis KL, Satpathy AT, Feldman SA, Sotillo E, Mackall CL. Klysz DD, et al. Among authors: keerthi v. bioRxiv [Preprint]. 2023 Apr 25:2023.04.21.537859. doi: 10.1101/2023.04.21.537859. bioRxiv. 2023. PMID: 37162847 Free PMC article. Updated. Preprint.
Non-viral chimeric antigen receptor (CAR) T cells going viral.
Balke-Want H, Keerthi V, Cadinanos-Garai A, Fowler C, Gkitsas N, Brown AK, Tunuguntla R, Abou-El-Enein M, Feldman SA. Balke-Want H, et al. Among authors: keerthi v. Immunooncol Technol. 2023 Mar 9;18:100375. doi: 10.1016/j.iotech.2023.100375. eCollection 2023 Jun. Immunooncol Technol. 2023. PMID: 37124148 Free PMC article. Review.
Ca2+-binding protein from Entamoeba histolytica (EhCaBP6) is a novel GTPase.
Verma D, Agarwal S, Keerthi V, Murmu A, Gourinath S, Bhattacharya A, Chary KR. Verma D, et al. Among authors: keerthi v. Biochem Biophys Res Commun. 2020 Jun 30;527(3):631-637. doi: 10.1016/j.bbrc.2020.04.141. Epub 2020 May 16. Biochem Biophys Res Commun. 2020. PMID: 32423808
16 results